期刊论文

中文

中国医学工程

1672-2019

2009

17

3

179-181

本校为第一机构

目的 探讨RUNX3蛋白在宫颈癌组织中的表达及其临床意义.方法 选取宫颈癌患者88例,以正常宫颈组织20例作为对照,应用SP免疫组化方法检测RUNX3蛋白的表达,分析其与宫颈癌的病理分级及临床分期的关系.结果 宫颈癌组织中RUNX3阴性、弱、中、强表达依次为56.8%(50/88)、22.7%(20/88)、17.0%(15/88)、3.4%(3/88),与正常宫颈组织相比,RUNX3在宫颈癌的表达存在显著下调(P

[ Objective ] To analyze the clinicopathological features of the expression of RUNX3 in human cervix cancer and evaluate its clinical significance in the progression of cervix cancer. [ Methods ] 88 patients with cervix cancer were examined for the expression of RUNX3 by SP immunohistochemistry. [Results] The negative, weak positive, moderate positive and strong positive expression rates of RUNX3 in 88 patients with the cervix cancer were 56.8% （50/88）, 22.7% （20/88）, 17.0% （15/88） and 3.4% （3/88）, respectively, which were significantly...