Rationally designed NIR-II excitable and endoplasmic reticulum-targeted molecular phototheranostics for imaging-guided enhanced photoimmunotherapy of triple-negative breast cancer

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Liu, Fen;Kang, Qiang;Xiao, Hao;Liu, Yinying;Tan, Sengyou;...

通讯作者：

Tan, Xiaofeng;Wu, Guilong;Yang, QL

作者机构：

[Xiao, Hao; Wu, Guilong; Liu, Fen; Tan, Xiaofeng; Wu, GL; Yang, Qinglai; Kang, Qiang; Tan, XF; Tan, Sengyou; Liu, Yinying] Univ South China, Affiliated Hosp 1, Dept Hepatopancreatobiliary Surg, Hengyang 421001, Hunan, Peoples R China.

[Xiao, Hao; Wu, Guilong; Liu, Fen; Tan, Xiaofeng; Wu, GL; Yang, Qinglai; Kang, Qiang; Tan, XF; Tan, Sengyou; Liu, Yinying] Univ South China, Canc Res Inst, Ctr Mol Imaging Probe, Hengyang Med Sch, Hengyang 421001, Hunan, Peoples R China.

[Fan, Kun; Peng, Jianchun; Liu, Fen] Univ South China, Affiliated Hosp 2, Dept Radiol, Hengyang 421001, Hunan, Peoples R China.

[Wu, Guilong; Tan, Xiaofeng; Wu, GL; Yang, Qinglai; Tan, XF] Univ South China, NHC Key Lab Birth Defect Res & Prevent, Hengyang 421001, Hunan, Peoples R China.

[Wu, Guilong; Tan, Xiaofeng; Wu, GL; Yang, Qinglai; Tan, XF] Univ South China, MOE Key Lab Rare Pediat Dis, Hengyang 421001, Hunan, Peoples R China.

通讯机构：

[Tan, XF; Yang, QL ; Wu, GL] U

Univ South China, Affiliated Hosp 1, Dept Hepatopancreatobiliary Surg, Hengyang 421001, Hunan, Peoples R China.

Univ South China, Canc Res Inst, Ctr Mol Imaging Probe, Hengyang Med Sch, Hengyang 421001, Hunan, Peoples R China.

Univ South China, NHC Key Lab Birth Defect Res & Prevent, Hengyang 421001, Hunan, Peoples R China.

Univ South China, MOE Key Lab Rare Pediat Dis, Hengyang 421001, Hunan, Peoples R China.

语种：

英文

关键词：

NIR-II;Phototheranostics;Endoplasmic reticulum;Triple-negative breast cancer;Intermolecular π–π stacking interaction

期刊：

Journal of Nanobiotechnology

ISSN：

1477-3155

年：

2025

卷：

期：

页码：

1-21

DOI：

10.1186/s12951-025-03282-5

基金类别：

This work was supported by the National Science Foundation of China (22374065), the Outstanding Youth Foundation of Hunan Province (2024JJ2047), the Key Research and Development Program of Hunan Province, China (2022SK2053), the Aid Program for Science and Technology Innovative Research Team in Higher Educational Institutions of Hunan Province, the Natural Science Foundation of Hunan Province of China (2024JJ6374, 2025JJ81013) and the Scientific Research Fund of Hunan Province Education Department (24B0427, 24B0393).

机构署名：

本校为第一且通讯机构

院系归属：

医学院

摘要：

Triple-negative breast cancer (TNBC) is a highly aggressive subtype of breast cancer characterized by an extremely poor prognosis. Photoimmunotherapy has emerged as a promising strategy for the treatment of TNBC. This approach works by selectively destroying tumor cells, releasing tumor-associated antigens, activating the immune system, and effectively inhibiting tumor proliferation and metastasis. However, the majority of current phototheranostic approaches are hindered by limited tissue penetration in the first near-infrared (NIR-I) and ultra...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Rationally designed NIR-II excitable and endoplasmic reticulum-targeted molecular phototheranostics for imaging-guided enhanced photoimmunotherapy of triple-negative breast cancer

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问