期刊论文

Mechanism and prevention strategy on heart injury of COVID-19

中文

中国动脉硬化杂志

1007-3949

2020

28

4

301-305

10.3969/j.issn.1007-3949.2020.04.007

国家自然科学基金(8167042481900424) 湖南省卫生计生委项目(B2016087,B20180058,B20180874) 湖南省自然科学基金项目(2018JJ2345、2019JJ40258、2019JJ50502和2015JJ2118)。

本校为第一机构

2019新型冠状病毒(2019-nCoV)以血管紧张素转换酶2(ACE2)为受体侵入细胞引起机体感染,所引起的"细胞因子风暴"是2019冠状病毒病(COVID-19)爆发和死亡的重要原因。临床资料显示,2019-nCoV除了累及呼吸系统外,还伴随着心脏损伤,如急性心肌损伤、心律失常和爆发性心肌炎等。文章主要阐述2019-nCoV对心脏损伤的主要表现和发病机制及其相关防治策略。

2019 novel coronavirus(2019-nCoV)invades cells with angiotensin converting enzyme 2(ACE2)as a receptor to cause infection,and the result of"cytokine storm"is the significant reason inducing coronavirus disease 2019(COVID-19)?s outbreak and death.Clinical data shows that 2019-nCoV is not only involved in the respiratory system,but also accompanied by heart injury,such as acute myocardial injury,arrhythmia and fulminant myocarditis.This review mainly describes the main manifestations,mechanism an...