The vascular endothelial cell( VEC) is a single layer of flat squamous epithelium covering the intima of the blood vessel. It constitutes a biological barrier to the blood vessel wall. It is not only a protective barrier but also produces some autocrine secretion. The substance is used to regulate homeostasis and vascular tone and has a variety of biological functions. VECsenescence can lead to vascular dysfunction,which is a major risk factor for cardiovascular system( CVS) and has a close relationship with cardiovascular disease( CVD). However,themechanism of VEC senescence and the effects o...
