期刊论文

中文

中国动脉硬化杂志

1007-3949

2018

26

10

973-979

10.3969/j.issn.1007-3949.2018.10.002

81770490:国家自然科学基金 81270360:国家自然科学基金 2014FJ2012:湖南省科技厅科技重点项目

本校为第一机构

动脉粥样硬化是一种慢性炎症性疾病,是血管壁对各种损伤的异常反应。虽然影响动脉粥样硬化的因素很多,但淋巴管在动脉粥样硬化中的作用一直被忽视。传统上认为淋巴管是将间质液回流至血液循环的通道。在早期的研究中,发现动脉粥样硬化周围存在大量淋巴管,但两者之间的关系一直不清楚。近期研究发现淋巴管不仅参与动脉炎症的起始和消退,在胆固醇逆转运中也发挥着积极作用。此外,改善淋巴功能或促进局部淋巴管生成似乎可以减轻动脉粥样硬化的进展。因此,研究淋巴管与动脉粥样硬化的关系对干预动脉粥样硬化的发生发展具有重要意义。文章介绍了淋巴管与动脉粥样硬化发生发展相关的炎症、胆固醇逆转运...

Atherosclerosis is a chronic inflammatory disease and an abnormal response of vascular walls to various injuries. Although there are many factors affecting atherosclerosis,the role of lymphatics in atherosclerosis has been neglected. Lymphatic vessels are the channels through which the interstitial fluid is returned to the blood circulation. Although a large number of lymphatic vessels have been found in atherosclerotic lesions,the relationship between the two is unclear. Recent studies have found that lymphatic vessels not only participate in the induction and solution of arterial inflammatio...