Osteoporosis and atherosclerosis are both widely prevalent in ageing population,and induce serious morbidities and death. There is growing evidence that osteoporosis and atherosclerosis have clinical interrelation. Experimental studies indicate that bone and arterial wall share some matrix proteins and factors,such as osteoprotegerin,osteopontin,matrix Gla protein,osteocalcin and low density lipoprotein receptor-related protein. And both diseases may have the same physiopathologic mechanism. The osteoprotegerin / receptor activator of nuclear f...
