Hydrogen sulfide is a toxic gas with rotten eggs taste. However, there were a large number of articles reported that hydrogen sulfide was the third gaseous signaling molecule after CO and NO in recent years. Hydrogen sulfide derived mainly from cystathionine b-synthase, cystathionine c-lyase and 3-Mercaptopyruvate sulfurtransferase enzyme, which had many roles such as blood vessel dilatation, regulating blood pressure, inhibiting vascular smooth muscle cell pro- liferation and low density lipoprotein (LDL) oxidative modification. Especially h...