Aim To explore the effect of arecoline （Are） on the formation of foam cells induced by the oxidized low density lipoprotein （ox-LDL） and analyze the possible mechanisms. Methods RAW 264.7 macrophages were incubated by ox-LDL （50 mg/L） for 48 h to induce foam cells. Arecoline （10-6mol/L, 10-Smol/L and 10-4mol/L） was added for 48 h at the same time. The cellular lipid accumulation was examined by oil red staining. The cellular con- tents of total cholesterol （TC） and free cholesterol （FC） were detected by high performance liquid chrom...
