Aim To investigate the effect of oxidized low density lipoprotein （ox-LDL） on ten-eleven-translocation 2 （TET2） expression and autophagy in human umbilical vein endothelial cells （HUVEC）. Methods After treatment with ox-LDL for 24 h, RT-PCR was used to detect mRNA expression of TET2. Western blot was used to detect protein ex- pression of TET2 and autophagic marker Beclin 1 and microtubule-associated protein light chain 3 （ LC3 ）. HUVEC were transfected with TEI2 siRNA, and then Beclin 1 and LC3 were detected by using Western blot. Resu...
