期刊论文

中文

中国动脉硬化杂志

1007-3949

2000

8

3

241-243

10.3969/j.issn.1007-3949.2000.03.014

:湖南省教育厅科学研究项目

本校为第一机构

为了研究胚胎期心脏心房钠尿肽的发生及变化规律 ,收集因孕妇自愿流产或引产的胚胎 6 5例 (经临床证实孕妇无心血管疾病 ) ,用放射免疫法同步测定胚胎心脏各部位心房钠尿肽的含量。结果发现于第 6周心房内心房钠尿肽开始出现 ,但其含量甚微 ,尔后其含量随胎龄的增长而增加 ;而心室内的心房钠尿肽含量在第 6周时较高 ,且其含量随胎龄的增长而减少 ,至足月时几乎消失。同一胎龄心房钠尿肽以右心耳含量最高 ,右心房含量高于左心房 ,左心室含量高于右心室。这一结果表明人胚胎心房钠尿肽于第 6周出现 ,且随胎龄的增长而增加 ;心室及室间隔内也含心房钠尿肽 ,其含量随胎龄的增长而减少。

Aim Study on the accurence and regluar patterns of atrial natriuretic factor (ANF) in the human heart befor birth. Methods Collection of 65 embryo cares from accidental abortionsor miscarriages or induced labour of the pregrant women with no cardiovascular disease in clinical diaynosio, measurement of the amount of ANF in different locations of the embryocal heart means of radioimmunoassay. Results ANF in the atria appeared in the sixth week ,but in a minute amount, increasing with the growth of the embryo, while the amount of ANF in the ventricals reached a rather higher level in the sixth we...