The efficient extraction of uranium from acid mining wastewater remains a significant challenge. In this study, a novel phospho-enriched polyamidoxime/alginate (PA/PAO/SA) gel beads was fabricated through a one-pot self-assembly method with calcium ions for crosslinking and used for efficient extraction of U(VI). Drawing on abundant functional groups, the PA/PAO/SA gel beads exhibited remarkable uranium extraction performance in acidic uranium-containing wastewater within the pH range of 2.5–5.5, and the removal rate of a 20 mg/L uranium-conta...