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Haemodynamic Effects on the Development and Stability of Atherosclerotic Plaques in Arterial Blood Vessel

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成果类型:
期刊论文
作者:
Lei, Weirui;Qian, Shengyou;Zhu, Xin;Hu, Jiwen
通讯作者:
Qian, SY;Hu, JW
作者机构:
[Qian, Shengyou; Lei, Weirui; Qian, SY] Hunan Normal Univ, Sch Phys & Elect, Changsha 410006, Peoples R China.
[Zhu, Xin] Univ South China, Hengyang Med Sch, Hengyang 421001, Peoples R China.
[Hu, JW; Hu, Jiwen] Univ South China, Sch Math & Phys, Hengyang 421001, Peoples R China.
通讯机构:
[Hu, JW ] U
[Qian, SY ] H
Hunan Normal Univ, Sch Phys & Elect, Changsha 410006, Peoples R China.
Univ South China, Sch Math & Phys, Hengyang 421001, Peoples R China.
语种:
英文
关键词:
Atherosclerosis;Necrotic core;Plaque stability;Finite-element method
期刊:
INTERDISCIPLINARY SCIENCES-COMPUTATIONAL LIFE SCIENCES
ISSN:
1913-2751
年:
2023
卷:
15
期:
4
页码:
616-632
基金类别:
This study was supported by the National Nature Science Foundation of China (No.12274200、11774088) and Hengyang science and technology plan projects (No.202250045335).
机构署名:
本校为通讯机构
院系归属:
数理学院
摘要:
Studying the formation and stability of atherosclerotic plaques in the hemodynamic field is essential for understanding the growth mechanism and preventive treatment of atherosclerotic plaques. In this paper, based on a multiplayer porous wall model, we established a two-way fluid–solidinteraction with time-varyinginlet flow. The lipid-rich necrotic core (LRNC) and stress in atherosclerotic plaque were described for analyzing the stability of atherosclerotic plaques during the plaque growth by solving advection–diffusion–reaction equations w...

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