期刊论文

中文

中国循环杂志

1000-3614

1997

12

6

436-438

本校为第一机构

目的：评价硝酸甘油（ＮＧ）对充血性心力衰竭患者血浆内皮素的影响。方法：应用放射免疫法测定３２例充血性心力衰竭患者和１７例健康人血浆内皮素浓度。充血性心力衰竭组含１７例冠心病和１５例非冠心病患者。观测ＮＧ静脉滴注前后内皮素、心率和血压的动态变化。结果：充血性心力衰竭组内皮素浓度为９３．８６±１３．４８ｐｇ／ｍｌ，较对照组（３８．１７±１７．２４ｐｇ／ｍｌ）显著升高（Ｐ〈０．００１）。内皮素升高的程度

? Objective:To evaluate the effect of intravenous nitroglycerine(NG) on plasma endothelin in patients with congestive heart failure. Methods:Thirty two patients with congestive heart failure (CHF)and 17 normal healthy control were studied.In the CHF group ,17 cases had coronary heart disease.The plasma endothelin (ET) was determined by radioimmuoassay before and after intravenous administration of nitroglycerin NG.Heart rate and blood pressure were also recorded. Results:The plasma ET in CHF group was significantly higher than normal contro...