The question, whether long-term treatment of arterial hypertension with inhibitors of the angiotensinconverting enzyme (ACE) is capable of modifying glucose tolerance or insulin sensitivity in type Ⅱ (non-insulin-dependent) diabetes, is still unsolved. We studied 14 moderately overweight type Ⅱ diabetic patients with essential hypertension in stable metabolic control after a run-in period and again after 3 months of antihypertensive treatment with ACE inhibitor, captopril. Glucose tolerance was tested with a 75 g oral glucose load and insulin...
