LncRNA: a new perspective on the study of neurological diseases

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Ma, Yun*;He, Siqi;Gu, Tianhe;Liu, Yixuan;He, Shuya;...

通讯作者：

Ma, Yun;Jiang, ZS;Ma, Y

作者机构：

[He, Shuya; Jiang, ZS; Liu, Yixuan; He, Siqi; Ma, Yun; Jiang, Zhisheng; Gu, Tianhe] Univ South China, Hengyang Med Sch, Inst Biochem & Mol Biol, Hengyang 421001, Peoples R China.

[Jiang, ZS; Ma, Yun; Jiang, Zhisheng] Univ South China, Hengyang Med Sch, Inst Cardiovasc Dis, Key Lab Arteriosclerol Hunan Prov,Hunan Int Sci &, Hengyang 421001, Peoples R China.

[Ma, Yun] Univ South China, Hengyang Med Sch, Key Lab Ecol Environm & Crit Human Dis Prevent Hu, Dept Educ, Hengyang 421001, Peoples R China.

[He, Shuya; Ma, Yun] Univ South China, Hunan Prov Cooperat Innovat Ctr Mol Target New Dr, Hengyang Med Sch, Hengyang 421001, Peoples R China.

通讯机构：

[Jiang, ZS ; Ma, Y; Ma, Y ] U

Univ South China, Hengyang Med Sch, Inst Biochem & Mol Biol, Hengyang 421001, Peoples R China.

Univ South China, Hengyang Med Sch, Inst Cardiovasc Dis, Key Lab Arteriosclerol Hunan Prov,Hunan Int Sci &, Hengyang 421001, Peoples R China.

Univ South China, Hengyang Med Sch, Key Lab Ecol Environm & Crit Human Dis Prevent Hu, Dept Educ, Hengyang 421001, Peoples R China.

Univ South China, Hunan Prov Cooperat Innovat Ctr Mol Target New Dr, Hengyang Med Sch, Hengyang 421001, Peoples R China.

语种：

英文

关键词：

Diseases of the nervous system;ceRNA;lncrna;microRNA

期刊：

Biochemical Society Transactions

ISSN：

1470-8752

年：

2022

卷：

期：

页码：

951-963

DOI：

10.1042/BST20211181

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81971087]; National Key Research and Development Project [2019YFA0801601]; Hunan Provincial Innovation Foundation for Postgraduate [CX2018B624]

机构署名：

本校为第一且通讯机构

院系归属：

医学院

药学与生物科学学院

摘要：

Long non-coding RNAs (lncRNAs) are a class of non-coding RNA with a length greater than 200 nt. It has a mRNA-like structure, formed by splicing after transcription, and contains a polyA tail and a promoter, of whom promoter plays a role by binding transcription factors. LncRNAs' sequences are low in conservation, and other species can only find a handful of the same lncRNAs as humans, and there are different splicing ways during the differentiation of identical species, with spatiotemporal expression specificity. With developing high-throughpu...

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