Identification of NCK1 as a novel downstream effector of STAT3 in colorectal cancer metastasis and angiogenesis

首页 > 成果 > 详情

认领

导出

下载 Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Zhang, Fan;Lu, Yan-Xia;Chen, Qing;Zou, Hui-Mei;Zhang, Jian-Ming;...

通讯作者：

Li, Xue-Nong

作者机构：

[Li, Xiao-Min; Li, Xue-Nong; Lin, Chun; Zhang, Wen-Juan; Zhang, Wei; Hu, Yu-Han; Zhang, Jian-Ming; Zhang, Fan; Lu, Yan-Xia] Southern Med Univ, Sch Basic Med Sci, Dept Pathol, 1023-1063 Shatai Rd, Guangzhou 510515, Guangdong, Peoples R China.

[Chen, Qing; Zhang, Jian-Ming] Southern Med Univ, Nanfang Hosp, Dept Surg, Guangzhou 510515, Guangdong, Peoples R China.

[Zou, Hui-Mei] Univ South China, Sch Nursing, Hengyang 421001, Peoples R China.

通讯机构：

[Li, Xue-Nong] S

Southern Med Univ, Sch Basic Med Sci, Dept Pathol, 1023-1063 Shatai Rd, Guangzhou 510515, Guangdong, Peoples R China.

语种：

英文

关键词：

*Angiogenesis;*Colorectal cancer;*Metastasis;*NCK1;*STAT3

期刊：

Cellular Signalling

ISSN：

0898-6568

年：

2017

卷：

页码：

67-78

DOI：

10.1016/j.cellsig.2017.04.020

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81272758, 81302158, 81502479]; Natural Science Foundation of Guangdong Province, ChinaNational Natural Science Foundation of Guangdong Province [2014A030310099]

机构署名：

本校为其他机构

院系归属：

护理学院

摘要：

Signal transducer and activator of transcription 3 (STAT3) is known to activate targets associated with invasion, proliferation, and angiogenesis in a wide variety of cancers. The adaptor protein NCK1 is involved in cytoskeletal movement and was identified as a STAT3-associated target in human tumors. However, the underlying molecular mechanism associated with colorectal cancer (CRC) metastasis is not yet completely understood. In this study, we report a novel STAT3 to NCK1 signaling pathway in colorectal cancer (CRC). We investigated the expre...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Identification of NCK1 as a novel downstream effector of STAT3 in colorectal cancer metastasis and angiogenesis

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问