The neutrophil-to-lymphocyte ratio, lymphocyte-to-monocyte ratio, and neutrophil-to-high-density-lipoprotein ratio are correlated with the severity of Parkinson\'s disease - 成果

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The neutrophil-to-lymphocyte ratio, lymphocyte-to-monocyte ratio, and neutrophil-to-high-density-lipoprotein ratio are correlated with the severity of Parkinson's disease

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Li, Fangyi;Weng, Guomei;Zhou, Hang;Zhang, Wenjie;Deng, Bin;...

通讯作者：

Zhu, Shuzhen;Wang, Q

作者机构：

[Zhu, Shuzhen; Li, Fangyi; Zhang, Wenjie; Deng, Bin; Zhu, SZ; Wang, Qing; Zhou, Hang; Wang, Q; Weng, Guomei; Luo, Yuqi] Southern Med Univ, Dept Neurol, Zhujiang Hosp, Guangzhou, Peoples R China.

[Li, Fangyi] Univ South China, Affiliated Changsha Cent Hosp, Hengyang Med Sch, Dept Neurol, Changsha, Peoples R China.

[Weng, Guomei] First Peoples Hosp Zhaoqing, Dept Neurol, Zhaoqing, Peoples R China.

[Tao, Xi] Hunan Normal Univ, Hunan Prov Peoples Hosp, Dept Neurol Rehabil, Affiliated Hosp 1, Changsha, Peoples R China.

[Deng, Mingzhu] Brain Hosp Hunan Prov, Peoples Hosp Hunan Prov 2, Dept Neurol, Changsha, Peoples R China.

通讯机构：

[Wang, Q ; Zhu, SZ] S

Southern Med Univ, Dept Neurol, Zhujiang Hosp, Guangzhou, Peoples R China.

语种：

英文

关键词：

Parkinson’s disease;inflammation;lymphocyte-to-monocyte ratio;neutrophil-to-high-density lipoprotein ratio;neutrophil-to-lymphocyte ratio

期刊：

FRONTIERS IN NEUROLOGY

ISSN：

1664-2295

年：

2024

卷：

页码：

1322228

DOI：

10.3389/fneur.2024.1322228

基金类别：

Initiated Foundation of Zhujiang Hospital

机构署名：

本校为其他机构

院系归属：

医学院

摘要：

BACKGROUND: Inflammation plays a pivotal role in the pathogenesis of Parkinson's disease (PD). However, the correlation between peripheral inflammatory markers and the severity of PD remains unclear. METHODS: The following items in plasma were collected for assessment among patients with PD (n = 303) and healthy controls (HCs; n = 303) were assessed for the neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte ratio (LMR) and neutrophil-to-high-density-lipoprotein ratio (NHR) in plasma, and neuropsychological assessments were perform...

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The neutrophil-to-lymphocyte ratio, lymphocyte-to-monocyte ratio, and neutrophil-to-high-density-lipoprotein ratio are correlated with the severity of Parkinson's disease

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