Endothelial to mesenchymal transition in atherosclerotic vascular remodeling

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Hao, Ya-Meng;Yuan, Hou-Qin;Ren, Zhong;Qu, Shun-Lin;Liu, Lu-Shan;...

通讯作者：

Jiang, Zhi-Sheng

作者机构：

[Jiang, Zhi-Sheng; Hao, Ya-Meng; Ren, Zhong; Qu, Shun-Lin; Yin, Kai; Yuan, Hou-Qin; Wei, Dang-Heng; Liu, Lu-Shan] Univ South, Key Lab Arteriosclerosis Hunan Prov, Inst Cardiovasc Dis, Hengyang City 421001, Hunan, Peoples R China.

[Yin, Kai] Univ South China, Med Sch, Res Lab Translat Med, Hengyang 421001, Peoples R China.

[Fu, Mingui] Univ Missouri, Sch Med, Shock Trauma Res Ctr, Dept Biomed Sci, Kansas City, MO 64108 USA.

[Jiang, Zhi-Sheng] Univ South China, Key Lab Arteriosclerol Hunan Prov, Inst Cardiovasc Dis, Hengyang 421001, Hunan, Peoples R China.

通讯机构：

[Jiang, Zhi-Sheng] U

Univ South China, Key Lab Arteriosclerol Hunan Prov, Inst Cardiovasc Dis, Hengyang 421001, Hunan, Peoples R China.

语种：

英文

关键词：

Atherosclerosis;Endothelial cell;Endothelial to mesenchymal transition;Vascular remodeling

期刊：

Clinica Chimica Acta

ISSN：

0009-8981

年：

2019

卷：

490

页码：

34-38

DOI：

10.1016/j.cca.2018.12.018

基金类别：

The work was supported by the National Natural Science Foundation of China ( 81670429 , 81470435 to ZS. Jiang) and “Double First-Class” project for innovative Group of Basic Medicine, University of South China (to ZS.Jiang).

机构署名：

本校为通讯机构

院系归属：

医学院

摘要：

Endothelial cells are the main components of the heart, blood vessels, and lymphatic vessels, which play an important role in regulating the physiological functions of the cardiovascular system. Endothelial dysfunction is involved in a variety of acute and chronic cardiovascular diseases. As a special type of epithelial-mesenchymal transition (EMT), endothelium to mesenchymal transition (EndMT) regulates the transformation of endothelial cells into mesenchymal cells accompanied by changes in the expression of various transcription factors and cytokines, which is closely related to vascular end...

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Endothelial to mesenchymal transition in atherosclerotic vascular remodeling

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