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Genetics of congenital heart disease

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成果类型:
期刊论文
作者:
Zhao, Yuanqin;Deng, Wei;Wang, Zhaoyue;Wang, Yanxia;Zheng, Hongyu;...
通讯作者:
Jiang, ZS
作者机构:
[Wang, Zhaoyue; Wang, Yanxia; Ren, Zhong; Jiang, ZS; Zhou, Kun; Zheng, Hongyu; Liu, Huiting; Xu, Qian; Jiang, Zhisheng; Bai, Le; Zhao, Yuanqin; Deng, Wei] Univ South China, Inst Cardiovasc Dis, Int Joint Lab Arteriosclerot Dis Res Hunan Prov, Key Lab Arteriosclerol Hunan Prov, Hengyang 421001, Peoples R China.
通讯机构:
[Jiang, ZS ] U
Univ South China, Inst Cardiovasc Dis, Int Joint Lab Arteriosclerot Dis Res Hunan Prov, Key Lab Arteriosclerol Hunan Prov, Hengyang 421001, Peoples R China.
语种:
英文
关键词:
Congenital heart disease;Gene detection techniques;Gene family;Neurodevelopment;Synergistic developmental abnormalities
期刊:
Clinica Chimica Acta
ISSN:
0009-8981
年:
2024
卷:
552
页码:
117683
基金类别:
Gene testing technology involves the detection of specific regions within DNA or RNA sequences to determine the presence, absence, or mutations of particular genes or gene groups. Its fundamental principles leverage the properties of DNA molecules, including their double-helix structure, base-pairing rules, encoding of genetic information, as well as mutations and polymorphisms, to analyze and understand DNA sequences. While every individual's DNA sequence is unique, there is approximately
机构署名:
本校为第一且通讯机构
院系归属:
医学院
摘要:
During embryonic development, the cardiovascular system and the central nervous system exhibit a coordinated developmental process through intricate interactions. Congenital heart disease (CHD) refers to structural or functional abnormalities that occur during embryonic or prenatal heart development and is the most common congenital disorder. One of the most common complications in CHD patients is neurodevelopmental disorders (NDD). However, the specific mechanisms, connections, and precise ways in which CHD co-occurs with NDD remain unclear. According to relevant research, both genetic and no...

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