期刊论文

Peptide-Based Metal Ion Sensors

中文

化学进展

1005-281X

2021

33

3

380-393

10.7536/PC200611

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [20471025, 21142003, 21977042]; Scientific Research Foundation of Liaocheng University [318011919]

本校为其他机构

多肽基金属离子传感器作为一种基于多肽序列而设计的新型传感器,越来越受到研究者的关注。多肽作为一类重要的生物小分子,具有合成方法成熟、简便、成本低,且能够以多齿配位状态与金属离子结合等优点。多肽基传感器对金属离子具有高灵敏性和高选择性,且可以通过调节多肽序列进一步优化。与其他类型传感器相比,多肽基金属离子传感器具有良好的水溶性、生物相容性以及低毒性,因而在环境检测和生物医学分析与诊断,尤其是金属离子成像等方面,有重要的应用前景。本文主要综述了近年来不同类型的多肽基金属离子传感器,包括基于紫外-可见吸收光谱法、荧光光谱法和电化学分析法等的研究进展,以及它们在一...

Peptide-based metal ion sensors,as a new type of sensor designed based on peptide sequences,have attracted more and more attention from researchers. As important small biological molecules, peptides have advantages of simple and well-developed synthetic methods with low costs, and can provide multidentate coordination to metal ions. Peptide-based sensors have high sensitivity and high selectivity to metal ions, and can be further optimized by adjusting the peptide sequence. Compared with other types of sensors, peptide-based metal ion sensors have good water solubility, biocompatibility, and l...