Endothelial dysfunction of syphilis: Pathogenesis

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成果类型：

期刊论文

作者：

Liu, Zhaoping;Zhang, Xiaohong;Xiong, Shun;Huang, Shaobin;Ding, Xuan;...

通讯作者：

Zhao, FJ;Liu, SQ

作者机构：

[Xiong, Shun; Zhao, Feijun; Liu, Shuangquan; Liu, Zhaoping; Ding, Xuan; Huang, Shaobin; Yao, Jiangchen; Zhang, Xiaohong; Xu, Man] Univ South China, Hengyang Med Coll, Inst Pathogen Biol, Hengyang, Peoples R China.

[Xiong, Shun; Zhao, Feijun; Liu, Shuangquan; Liu, Zhaoping; Ding, Xuan; Huang, Shaobin; Yao, Jiangchen; Zhang, Xiaohong; Xu, Man] Univ South China, Hengyang Med Coll, Key Lab Special Pathogen Prevent & Control Hunan P, Hengyang, Peoples R China.

[Xiong, Shun; Zhao, Feijun; Liu, Shuangquan; Liu, Zhaoping; Ding, Xuan; Huang, Shaobin; Yao, Jiangchen; Zhang, Xiaohong; Xu, Man] Univ South China, Affiliated Hosp 1, Hengyang Med Coll, Dept Clin Lab Med, Hengyang, Peoples R China.

[Zhao, Feijun; Zhao, FJ] Univ South China, Hengyang Med Coll, Inst Pathogen Biol, Hengyang 421001, Peoples R China.

[Zhao, Feijun; Zhao, FJ] Univ South China, Hengyang Med Coll, Key Lab Special Pathogen Prevent & Control Hunan P, Hengyang 421001, Peoples R China.

通讯机构：

[Zhao, FJ ; Liu, SQ ] U

Univ South China, Hengyang Med Coll, Inst Pathogen Biol, Hengyang 421001, Peoples R China.

Univ South China, Hengyang Med Coll, Key Lab Special Pathogen Prevent & Control Hunan P, Hengyang 421001, Peoples R China.

Univ South China, Affiliated Hosp 1, Hengyang Med Sch, Inst Microbiol & Infect Dis,Dept Clin Lab Med, Hengyang 421001, Peoples R China.

语种：

英文

期刊：

Journal of the European Academy of Dermatology and Venereology

ISSN：

0926-9959

年：

2024

DOI：

10.1111/jdv.19899

基金类别：

Scientific Research and Innovation Project of Postgraduates in Hunan Province

机构署名：

本校为第一且通讯机构

院系归属：

医学院

摘要：

Treponema pallidum is the causative factor of syphilis, a sexually transmitted disease (STD) characterized by perivascular infiltration of inflammatory cells, vascular leakage, swelling and proliferation of endothelial cells (ECs). The endothelium lining blood and lymphatic vessels is a key barrier separating body fluids from host tissues and is a major target of T. pallidum. In this review, we focus on how T. pallidum establish intimate interactions with ECs, triggering endothelial dysfunction such as endothelial inflammation, abnormal repai...

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Endothelial dysfunction of syphilis: Pathogenesis

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