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Determination of Gatifloxacin in Milk and Biological Fluids by Inhibitory Resonance Fluorescence Spectrometry

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成果类型:
期刊论文
作者:
Tan, Jinghui;Li, Guirong*;Yang, Huixian;Wang, Yongsheng;Zhou, Dejun
通讯作者:
Li, Guirong
作者机构:
[Wang, Yongsheng; Zhou, Dejun; Li, Guirong; Yang, Huixian; Tan, Jinghui] Univ South China, Coll Publ Hlth, Hengyang 421001, Peoples R China.
通讯机构:
[Li, Guirong] U
Univ South China, Coll Publ Hlth, Hengyang 421001, Peoples R China.
语种:
英文
关键词:
Gatifloxacin;Inhibition kinetics;Micelles sensitize;Resonance fluorescence;Rhodamin 6G
期刊:
Analytical Letters
ISSN:
0003-2719
年:
2013
卷:
46
期:
3
页码:
473-487
基金类别:
Received 25 June 2012; accepted 16 August 2012. The authors gratefully acknowledge the support of the Science Foundation of Hengyang, China (No. 2005KS01-018). Address correspondence to Guirong Li, College of Public Health, University of South China, Hengyang 421001, P. R. China. E-mail: liguirong525@126.com
机构署名:
本校为第一且通讯机构
院系归属:
公共卫生学院
摘要:
A novel method for the determination of trace gatifloxacin was established by resonance fluorescence techniques. It was based on the fact that oxidation of rhodamin 6G by hydrogen peroxide and Cu2+ was inhibited by gatifloxacin in Tris-HCl buffer medium and in presence of cetyl trimethyl ammonium bromide. The enhanced intensity (ΔF) of resonance fluorescence at 540 nm was proportional to the concentration of gatifloxacin in the range of 9.8 × 10-3 - 1.75 μg mL-1. The limit of detection was 2.9 ng mL-1 and the average recovery was 101.8% (n =...

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