期刊论文

Zheng, Xing

英文

Medicinal Chemistry Research

1054-2523

2010

19

9

1296-1306

10.1007/s00044-009-9271-z

Chinese Ministry of EducationMinistry of Education, China [20809]; Hunan Provincial Education DepartmentHunan Provincial Education Department [07B065]; Science and Technology Bureau of Hunan Province [2007FJ4155]; Hunan Provincial Natural Science FoundationNatural Science Foundation of Hunan Province [07JJ6157]

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A series of genistein derivatives was prepared and tested in vitro against leukocythemia (HL-60), colorectal adenocarcinoma (HT-29), and human gastric adenocarcinoma (SGC-7901) cell lines. Among these derivatives, 4′,5-di-n-octoxy-7-gem-difluoromethylenegenistein, 9f, had the strongest activity against HL-60, HT-29, and SGC-7901 cells.[Figure not avai...