Bak Foong pills combined with metformin in the treatment of a polycystic ovarian syndrome rat model

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成果类型：

期刊论文

作者：

Liu, Wenhui;Liu, Wenpei;Fu, Yuling;Wang, Yan;Zhang, Yuanzhen*

通讯作者：

Zhang, Yuanzhen

作者机构：

[Liu, Wenhui; Zhang, Yuanzhen; Wang, Yan] Wuhan Univ, Zhongnan Hosp, Ctr Reprod Med, Wuhan 430071, Hubei, Peoples R China.

[Liu, Wenpei] Univ South China, Peoples Hosp Chenzhou 1, Translat Med Inst, Chenzhou 423000, Hunan, Peoples R China.

[Fu, Yuling] Second Hosp Yinzhou, Dept Obstet & Gynecol, Ningbo 315000, Zhejiang, Peoples R China.

[Zhang, Yuanzhen] Wuhan Univ, Zhongnan Hosp, Ctr Reprod Med, 169 East Lake Rd, Wuhan 430071, Hubei, Peoples R China.

通讯机构：

[Zhang, Yuanzhen] W

Wuhan Univ, Zhongnan Hosp, Ctr Reprod Med, 169 East Lake Rd, Wuhan 430071, Hubei, Peoples R China.

语种：

英文

关键词：

Bak Foong pills;cytochrome P450 cholesterol side-chain cleavage enzyme;insulin-like factor-1;metformin;polycystic ovarian syndrome

期刊：

ONCOLOGY LETTERS

ISSN：

1792-1074

年：

2015

卷：

期：

页码：

1819-1825

DOI：

10.3892/ol.2015.3466

基金类别：

Hubei Provincial Health Department [JBX3022]

机构署名：

本校为其他机构

院系归属：

医学院

摘要：

The aim of the present study was to investigate the treatment effects and associated mechanism of Bak Foong pills (BFPs) combined with metformin in the treatment of polycystic ovarian syndrome (PCOS). BFPs and/or metformin were administrated to treat the PCOS rats, and the weights and morphologies of the ovary, uterus and adrenal gland were measured. The levels of fasting blood glucose (FBG), serum testosterone (T), luteinizing hormone, fasting insulin (FIN) and insulin‑like growth factor‑1 were also measured, and the homeostasis model assess...

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Bak Foong pills combined with metformin in the treatment of a polycystic ovarian syndrome rat model

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