Challenging role of Wnt5a and its signaling pathway in cancer metastasis (review)

首页 > 成果 > 详情

认领

导出

下载 Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Zhu, Neng;Qin, Li*;Luo, Zhigang;Guo, Qiong;Yang, Luoyan;...

通讯作者：

Qin, Li

作者机构：

[Guo, Qiong; Zhu, Neng; Yang, Luoyan] Cent S Univ, Xiangya Hosp 2, Dept Urol, Changsha 410011, Hunan, Peoples R China.

[Luo, Zhigang; Zhu, Neng] South China Univ, Affiliated Hosp 2, Dept Urol, Hengyang 421001, Hunan, Peoples R China.

[Qin, Li] Univ South China, Inst Pharm & Pharmacol, Hengyang 421001, Hunan, Peoples R China.

[Liao, Duanfang; Qin, Li] Hunan Univ Chinese Med, Sch Pharm, Changsha 410208, Hunan, Peoples R China.

[Qin, Li] Univ South China, Inst Pharm & Pharmacol, 28 Changsheng West Rd, Hengyang 421001, Hunan, Peoples R China.

通讯机构：

[Qin, Li] U

Univ South China, Inst Pharm & Pharmacol, 28 Changsheng West Rd, Hengyang 421001, Hunan, Peoples R China.

语种：

英文

关键词：

Wnt5a;cancer;metastasis;signaling pathway

期刊：

EXPERIMENTAL AND THERAPEUTIC MEDICINE

ISSN：

1792-0981

年：

2014

卷：

期：

页码：

3-8

DOI：

10.3892/etm.2014.1676

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81000946, 81270359]; Youth Project of the Educational Department of Hunan Province [10B090]; Construct Program of the Key Discipline in Hunan province

机构署名：

本校为通讯机构

院系归属：

药学与生物科学学院

摘要：

Wnt5a is a noncanonical signaling member of the wingless-related/mouse mammary tumor virus integration family, which is involved in a wide range of cellular processes, particularly in cancer development and metastasis. Accumulating evidence indicates that Wnt5a exhibits paradoxical effects in various types of cancer metastasis. Therefore, the Wnt5a signaling cascade in cancer metastasis appears to be complex and may depend on binding receptors, downstream effectors, exogenous inhibitors and tumor microenvironments, as well as the extracellular matrix, particularly cell/tissue-tropic contexts. ...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Challenging role of Wnt5a and its signaling pathway in cancer metastasis (review)

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问