Copper-64 is a radioisotope of medical interest that could be used for positron emission tomography imaging and targeted radiotherapy of cancer. In this work, we investigated the possibility of producing the ~(64)Cu isotope through a ~(65)Cu(γ,n) reaction using high-intensity c-beams produced at the Extreme Light Infrastructure- Nuclear Physics facility (ELI-NP). The specific activity for ~(64)Cu was obtained as a function of target geometry, irradiation time, and electron beam energy, which translates into γ-beam energy. Optimized conditions...