Background: AT-rich interactive domain 1A gene (ARID1A) had been reported to act as a tumor suppressor in gastric cancer (GC), and reduced expression of ARID1A is significantly correlated with lymphatic invasion and lymph node metastasis. However, its diagnostic value in GC remains unknown. The aim of this study was to detect the expression of serum ARID1A and investigate its diagnostic value in GC. Methods: ARID1A mRNA and protein expression were assessed in 120 GC serum samples and 70 healthy control samples by quantitative real-time polymerase chain reaction (qRT-PCR) and ELISA, respectivel...