This study was supported by the Natural Science Foundation of Hunan Province (No. 2022JJ40518), the Changsha Natural Science Foundation (grant numbers kq2014023 and kq2202052), 2020 Medical and Health Science and Technology Plan Project of Baiyun District, Guangzhou, Guangdong Province (No. 2020-YL-002) and General Research Project of Changsha Central Hospital (YNKY202224).