Host factors influencing sexual differentiation and transmission of Plasmodium: A comprehensive review

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成果类型：

期刊论文

作者：

Li, Yanlin;Tang, Jingjing;Tang, Wei;Liu, Cong;Li, Zhenkui

通讯作者：

Li, ZK

作者机构：

[Tang, Jingjing; Tang, Wei; Li, Yanlin; Li, Zhenkui] Univ South China, Inst Pathogen Biol, Sch Basic Med Sci, Hengyang Med Sch, Hengyang 421001, Hunan, Peoples R China.

[Tang, Jingjing; Tang, Wei; Li, Yanlin; Li, Zhenkui] Univ South China, Sch Basic Med Sci, Hengyang Med Sch, Key Lab Special Pathogen Prevent & Control Hunan P, Hengyang 421001, Hunan, Peoples R China.

[Liu, Cong] Univ South China, Sch Publ Hlth, Hengyang Med Sch, Dept Hlth Inspect & Quarantine, Hengyang 421001, Hunan, Peoples R China.

通讯机构：

[Li, ZK ] U

Univ South China, Inst Pathogen Biol, Sch Basic Med Sci, Hengyang Med Sch, Hengyang 421001, Hunan, Peoples R China.

Univ South China, Sch Basic Med Sci, Hengyang Med Sch, Key Lab Special Pathogen Prevent & Control Hunan P, Hengyang 421001, Hunan, Peoples R China.

语种：

英文

关键词：

Host factors;Plasmodium;Sexual differentiation;Vertebrate-to-mosquito transmission

期刊：

Acta Tropica

ISSN：

0001-706X

年：

2025

卷：

266

页码：

107634

DOI：

10.1016/j.actatropica.2025.107634

基金类别：

declarations This work was supported by grants from the National Natural Science Foundation of China (grant number 32000445 ), the Natural Science Foundation of Hunan Province (grant number 2022JJ40368 ), and the Scientific Research Project of Hunan Education Department (grant number 23B0403). CRediT authorship contribution statement Yanlin Li: Writing – original draft, Conceptualization. Jingjing Tang: Writing – original draft, Conceptualization. Wei Tang: Writing – review & editing. Cong Liu: Writing – review & editing. Zhenkui Li: Writing – review & editing, acquisition, Conceptualization.

机构署名：

本校为第一且通讯机构

院系归属：

医学院

公共卫生学院

摘要：

Malaria, a severe parasitic disease caused by Plasmodium infections, remains a major global health challenge. Efforts to eradicate malaria are complicated by the parasite’s intricate life cycle , which alternates between vertebrate hosts and mosquito vectors. Host-derived factors and parasite-sourced components exert crucial roles in regulating this biological process . This review explores the critical role of host-derived factors in shaping Plasmodium sexual differentiation and transmission. We examine how vertebrate and mosquito host-specif...

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Host factors influencing sexual differentiation and transmission of Plasmodium: A comprehensive review

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