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Host-similar fragments in the African swine fever virus genome: distribution, functions, and evolution

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成果类型:
期刊论文
作者:
Zhu, Zhaozhong;Li, Na;Sun, Qin;Long, Xizi;Wang, Tao;...
通讯作者:
Zhu, ZZ;Qiu, HJ
作者机构:
[Zhu, Zhaozhong; Li, Na; Sun, Qin; Long, Xizi] Univ South China, Sch Publ Hlth, Hengyang Med Sch, Hengyang 421001, Peoples R China.
[Qiu, Hua-Ji; Wang, Tao; Qiu, HJ] Chinese Acad Agr Sci, Harbin Vet Res Inst, State Key Lab Anim Dis Control & Prevent, Natl African Swine Fever Para Reference Lab,Natl H, Harbin, Peoples R China.
通讯机构:
[Zhu, ZZ ] U
[Qiu, HJ ] C
Univ South China, Sch Publ Hlth, Hengyang Med Sch, Hengyang 421001, Peoples R China.
Chinese Acad Agr Sci, Harbin Vet Res Inst, State Key Lab Anim Dis Control & Prevent, Natl African Swine Fever Para Reference Lab,Natl H, Harbin, Peoples R China.
语种:
英文
关键词:
African swine fever virus;host-similar fragments;similarity network;evolution;recombination
期刊:
VETERINARY RESEARCH
ISSN:
0928-4249
年:
2025
卷:
56
期:
1
页码:
1-11
基金类别:
This work was supported by the PhD Scientific Research Start-up Fund of the University of South China (5524QD075), the National Natural Science Foundation of China (U20 A2060) (HJQ), and the Heilongjiang Provincial Natural Science Foundation of China (TD2023 C007) (HJQ).
机构署名:
本校为第一且通讯机构
院系归属:
公共卫生学院
摘要:
African swine fever virus (ASFV) predominantly infects Argasidae and suids, resulting in high morbidity and mortality in pigs. Despite the crucial role that viral sequences resembling those of the host play in the virus's survival, there are limited comprehensive studies on the genomic similarities between ASFV and its hosts. Consequently, this study employs homology analysis to construct a similarity network between ASFV and its hosts (Argasidae and suids), investigating the distribution, function, evolution, and origins of these similar sequences in ASFV. Our findings indicate that the host-...

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