Identification of the major functional proteins of prokaryotic lipid droplets

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成果类型：

期刊论文

作者：

Ding, Yunfeng;Yang, Li;Zhang, Shuyan;Wang, Yang;Du, Yalan;...

通讯作者：

Steinbuechel, Alexander

作者机构：

[Yang, Fuquan; Pu, Jing; Zhang, Huina; Yang, Li; Ding, Yunfeng; Zhang, Shuyan; Wang, Yang; Peng, Gong; Du, Yalan; Hang, Haiying; Liu, Pingsheng; Chen, Yong; Yu, Jinhai; Wu, Peng] Inst Biophys, Natl Lab Biomacromol, Beijing, Peoples R China.

[Steinbuechel, Alexander] King Abdulaziz Univ, Jeddah 21413, Saudi Arabia.

[Pu, Jing; Yang, Li; Ding, Yunfeng; Wang, Yang; Peng, Gong; Yu, Jinhai] Chinese Acad Sci, Grad Univ, Beijing, Peoples R China.

[Du, Yalan] Univ S China, Dept Histol & Embryol, Hengyang, Hunan, Peoples R China.

[Yang, Hongyuan] Univ New S Wales, Sch Biotechnol & Biomol Sci, Sydney, NSW, Australia.

通讯机构：

[Steinbuechel, Alexander] K

King Abdulaziz Univ, Jeddah 21413, Saudi Arabia.

语种：

英文

关键词：

Apolipoprotein;Microorganism lipid droplet small;Proteomics;Rhodococcus RHA1

期刊：

Journal of Lipid Research

ISSN：

0022-2275

年：

2012

卷：

期：

页码：

399-411

DOI：

10.1194/jlr.M021899

基金类别：

Ministry of Science and Technology of ChinaMinistry of Science and Technology, China [2009CB919000, 2010CB833703, 2011CBA00900]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [30871229, 30971431, 31000365]

机构署名：

本校为其他机构

院系归属：

医学院

摘要：

Storage of cellular triacylglycerols (TAGs) in lipid droplets (LDs) has been linked to the progression of many metabolic diseases in humans, and to the development of biofuels from plants and microorganisms. However, the biogenesis and dynamics of LDs are poorly understood. Compared with other organisms, bacteria seem to be a better model system for studying LD biology, because they are relatively simple and are highly efficient in converting biomass to TAG. We obtained highly purified LDs from Rhodococcus sp. RHA1, a bacterium that can produce...

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Identification of the major functional proteins of prokaryotic lipid droplets

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