Angiogenesis in skin injury repair: mechanisms, regulation, and therapeutic strategies

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成果类型：

期刊论文

作者：

Mao, Jingyi;Lin, Zhirou;Pan, Ziyun;Huang, Yan;Luo, Yanhua;...

通讯作者：

Hu, Y

作者机构：

[Mao, Jingyi; Lin, Zhirou; Pan, Ziyun; Huang, Yan; Luo, Yanhua; Hu, Yin] Univ South China, Affiliated Hosp 1, Hengyang Med Sch, Dept Metab & Endocrinol, Hengyang 421001, Hunan, Peoples R China.

[Yin, Hao] Univ South China, Affiliated Hosp 1, Hengyang Med Sch, Dept Rehabil Med, Hengyang 421001, Hunan, Peoples R China.

[Yin, Hao; Xie, Hui] Cent South Univ, Xiangya Hosp, Dept Orthoped, Changsha 410008, Hunan, Peoples R China.

[Xie, Hui] Cent South Univ, Xiangya Hosp, Movement Syst Injury & Repair Res Ctr, Changsha 410008, Hunan, Peoples R China.

通讯机构：

[Hu, Y ] U

Univ South China, Affiliated Hosp 1, Hengyang Med Sch, Dept Metab & Endocrinol, Hengyang 421001, Hunan, Peoples R China.

语种：

英文

关键词：

Angiogenesis;Skin injury;Wound healing;Cytokine;Inflammatory response

期刊：

ARCHIVES OF DERMATOLOGICAL RESEARCH

ISSN：

0340-3696

年：

2025

卷：

317

期：

页码：

1-19

DOI：

10.1007/s00403-025-04424-3

基金类别：

the Project of Hunan Provincial Social Science Achievement Review Committee [82000845]; National Natural Science Foundation of China [2021JJ40492]; Hunan Province Natural Science Foundation of China [24A0311]; Scientific Research Fund of Hunan Provincial Education Department [XSP22YBC361]; Project of Hunan Provincial Social Science Achievement Review Committee

机构署名：

本校为第一且通讯机构

摘要：

Skin injury refers to the disruption of skin integrity, resulting in the loss of normal tissue, which can occur due to wounds, diseases, or surgeries. The repair of skin injuries is a highly regulated process involving cell migration, proliferation, collagen matrix deposition, and tissue remodeling, all of which are intricately linked to inflammation and angiogenesis. Angiogenesis-the formation of new blood vessels-plays a pivotal role in this process by ensuring the delivery of oxygen and nutrients that are essential for healing. Key angiogenic factors, such as vascular endothelial growth fac...

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Angiogenesis in skin injury repair: mechanisms, regulation, and therapeutic strategies

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