The present study aimed to investigate the association of the invasiveness of colon cancer (CC) with the expression of CCAAT/enhancer binding protein alpha (C/EBPalpha). Immunohistochemistry was performed to determine the expression of C/EBPalpha in the cancer and adjacent tissue samples from 48 patients with CC. A pCDGFP-C/EBPalpha eukaryotic expression vector was constructed, and a wound-healing assay was performed to observe the effect of transfection on the migration of SW480 cells. In addition, the expression levels of tumor invasion-associated proteins, including Kruppel-like factor 5 (K...
