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Polyhydroxylated Steroidal Glycosides from Paris polyphylla

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成果类型:
期刊论文
作者:
Kang, Li-Ping;Liu, Yi-Xun;Eichhorn, Tolga;Dapat, Else;Yu, He-shui;...
通讯作者:
Ma, Bai-Ping
作者机构:
[Liu, Chao; Liu, Yi-Xun; Zhao, Yang; Ma, Bai-Ping; Kang, Li-Ping; Yu, He-shui; Xiong, Cheng-Qi] Beijing Inst Radiat Med, Beijing 100850, Peoples R China.
[Kang, Li-Ping; Yu, He-shui] Tianjin Univ Tradit Chinese Med, Tianjin 300193, Peoples R China.
[Liu, Yi-Xun] Univ S China, Inst Pharmacol & Pharm, Hengyang 421001, Peoples R China.
[Dapat, Else; Eichhorn, Tolga; Efferth, Thomas] Univ Main, Inst Pharm & Biochem, Dept Pharmaceut Biol, D-55128 Mainz, Germany.
通讯机构:
[Ma, Bai-Ping] B
Beijing Inst Radiat Med, Beijing 100850, Peoples R China.
语种:
英文
关键词:
cell lines;chemical structure;cytotoxicity;glycosides;human diseases;rhizomes;saponins;man;Paris polyphylla;Homo;Hominidae;Primates;mammals;vertebrates;Chordata;animals;eukaryotes;Paris;Liliaceae;Trilliaceae;Liliales;monocotyledons;angiosperms;Spermatophyta;plants;heterosides
期刊:
JOURNAL OF NATURAL PRODUCTS
ISSN:
0163-3864
年:
2012
卷:
75
期:
6
页码:
1201-1205
基金类别:
Municipal Natural Science Foundation of BeijingBeijing Natural Science Foundation [7090001]; NSFC-Union Foundation of Yunnan Province [U10132601]
机构署名:
本校为其他机构
院系归属:
药学与生物科学学院
摘要:
Three new steroidal saponins, parisyunnanosides G-I (1-3), one new C 21 steroidal glycoside, parisyunnanoside J (4), and three known compounds, padelaoside B (5), pinnatasterone (6), and 20-hydroxyecdyson (7), were isolated from the rhizomes of Paris polyphylla Smith var. yunnanensis. Compounds 1 and 3 have unique trisdesmoside structures that include a C-21 β-D-galactopyranose moiety. All compounds were evaluated for their cytotoxicity against human CCRF leukemia cells. © 2012 Amer...

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