Integrative metabolomics highlights gut microbiota metabolites as novel NAFLD-related candidate biomarkers in children

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Luo, Jiayou;Luo, Miyang;Kaminga, Atipatsa C.;Wei, Jia;Dai, Wen;...

通讯作者：

Pan, XF

作者机构：

[Pan, Xiongfeng; Luo, Jiayou] Hunan Childrens Hosp, Pediat Res Inst Hunan Prov, Changsha, Peoples R China.

[Pan, Xiongfeng; Luo, Jiayou; Yao, Zhenzhen; Luo, Miyang; Dai, Wen; Xiao, Xiang; Wei, Jia; Duan, Yamei; Ouyang, Sisi; Liu, Yixu] Cent South Univ, Xiangya Sch Publ Hlth, Dept Maternal & Child Hlth, Changsha, Peoples R China.

[Luo, Miyang] Cent South Univ, Xiangya Sch Publ Hlth, Dept Epidemiol & Hlth Stat, Changsha, Peoples R China.

[Luo, Miyang] Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore, Singapore.

[Kaminga, Atipatsa C.] Mzuzu Univ, Dept Math & Stat, Mzuzu, Malawi.

通讯机构：

[Pan, XF ] H

Hunan Childrens Hosp, Pediat Res Inst Hunan Prov, Changsha, Peoples R China.

Cent South Univ, Xiangya Sch Publ Hlth, Dept Maternal & Child Hlth, Changsha, Peoples R China.

语种：

英文

关键词：

metabolomic;gut microbiota;non-alcoholic fatty liver disease;children;biomarker

期刊：

MICROBIOLOGY SPECTRUM

ISSN：

2165-0497

年：

2024

卷：

期：

页码：

e0523022

DOI：

10.1128/spectrum.05230-22

基金类别：

MOST | National Natural Science Foundation of China#&#&#81872641, 2021JJ30901 MOST | National Natural Science Foundation of China#&#&#2022JJ40668 Children's Hospital of Xiangya Medical College Project#&#&#2024GZPY04

机构署名：

本校为其他机构

院系归属：

公共卫生学院

摘要：

Altered gut microbiota and metabolites are important for non-alcoholic fatty liver disease (NAFLD) in children. We aimed to comprehensively examine the effects of gut metabolites on NAFLD progression. We performed integrative metabolomics (untargeted discovery and targeted validation) analysis of non-alcoholic fatty liver (NAFL), non-alcoholic steatohepatitis (NASH), and obesity in children. Fecal samples were collected from 75 subjects in the discovery cohort (25 NAFL, 25 NASH, and 25 obese control children) and 145 subjects in an independent ...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Integrative metabolomics highlights gut microbiota metabolites as novel NAFLD-related candidate biomarkers in children

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问