Temperature may affect the production of saxitoxin (STX) and its derivatives (STXs); however, this is still contro-versial. Further, STX-biosynthesis gene regulation and the relation of its toxicity with temperature are not clearly understood. In the present study, we evaluated the effects of different temperatures (12 degrees C, 16 degrees C, and 20 degrees C) on the growth, toxin profiles, and expression of two core STX-biosynthesis genes, sxtA and sxtG, in the toxic dinofla-gellate Alexandrium pacificum Alex05, isolated from Korean coasts. We found that temperature significantly af-fected c...
