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Local Magnetic Nanoparticle Delivery in Microvasculature

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成果类型:
期刊论文
作者:
Guo Ping*;Li Xin-Xia;Xiong Ping;He Ji-Shan
通讯作者:
Guo Ping
作者机构:
[He Ji-Shan; Xiong Ping; Guo Ping] Cent S Univ, Sch Infophys & Geomat Engn, Changsha 410083, Peoples R China.
[Li Xin-Xia; Guo Ping] Univ S China, Dept Nucl Phys, Hengyang 421001, Peoples R China.
通讯机构:
[Guo Ping] C
Cent S Univ, Sch Infophys & Geomat Engn, Changsha 410083, Peoples R China.
语种:
英文
关键词:
field emission;molybdenum dioxide;enhancement factor
关键词(中文):
磁性纳米粒子;人体微血管;磁流体;磁场定位
期刊:
中国物理快报:英文版
ISSN:
0256-307X
年:
2009
卷:
26
期:
1
页码:
368-371
基金类别:
Supported by the National Natural Science Foundation of China under Grant No 30371626, the Scientific Research Foundation of the Science and Technology Department of Hunan Province under Grant No 2008FJ3084.
机构署名:
本校为其他机构
院系归属:
国防科学技术学院
摘要:
The transport and capture of therapeutic magnetic nanoparticles in human microvasculature is studied numerically. The nanoparticles are injected into a vascular system upstream from malignant tissue, and are captured at the tumour site with the aid of a local applied magnetic field positioned outside the body. Taking into account the dominant magnetic and fluidic forces on the particles, our study shows that the nanoparticles can be directed to and concentrated at the desired zone that is within a few centimetres from the surface of the body. In addition, influence of the particles size, avera...

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