期刊论文

Yan, X.-M.(yanxueming88@126.com)

中文

分子催化

1001-3555

2013

27

2

145-151

10.16084/j.cnki.issn1001-3555.2013.02.006

湖南省教育厅科学研究资助项目（11C1084） 湖南省科技计划项目（2010FJ3014） 南华大学博士启动基金项目（2012XQD008）

本校为第一且通讯机构

研究开发了一个实用高效的钯铜共催化体系,1%Pd(OAc)_2与10%CuCl_2.2H_2O双金属组合催化剂在弱碱和0.5 equiv PPh_3配体存在下,顺利催化苯并唑类杂环与各种芳基溴的直接芳基化,并得到良好的收率.该钯铜共催化体系具有钯催化计量低、配体廉价易得、底物适用范围广、反应条件温和等特点.

A practical, efficient palladium\copper cocatalytic system has been developed. With only 1% Pd(OAc)2, 10% CuCl2·2H2O, 0.5 equiv of inexpensive PPh3 as ligand, and K2CO3 as the base, the direct arylation of benzoazoles with aryl bromides could be performed smoothly and afforded the desired arylated benzoazoles in good yields. The cocatalytic system has the property of low catalyst loading, simple ligand, ...