The forming principle of mesoporous silica(MS) and the adsorption mechanism of MS materials on heavy metals and radionuclides were expounded. The research progress of functionalized MS materials in radioactive wastewater treatment was described,a nd the treatment of radionuclides such as Co,Cs,Sr, and U by the most common functional groups with surface functionalization was discussed. The factors impacting the treatment of nuclide by MS adsorbents, such as morphology of MS, functional groups, types of nuclides,and adsorption conditions,as well as the issues existing in the functionalization re...