期刊论文

Haibo, M.

中文

中华小儿外科杂志

0253-3006

2022

43

9

835-844

10.3760/cma.j.cn421158-20210710-00344

Hunan Provincial Key R&D Program (2020SK2113); Hunan Provincial Clinical Medical Research Center for Pediatric Extremity Deformity (2019SK4006); General project of Hunan Provincial Health Commission (20200021).

本校为第一机构

目的比较先天性胫骨假关节（congenital pseudarthrosis of the tibia, CPT）合并神经纤维瘤病Ⅰ型（neurofibromatosis type 1, NF1）和CPT不合并NF1病变骨膜的组织病理特点有无差异。方法收集2016年9月至2020年12月在湖南省儿童医院骨科接受治疗的CPT合并NF1患儿20例（NF1-CPT组）、CPT不合并NF1患儿20例（非NF1-CPT组）病变骨膜标本, 收集2021年12月至2021年1月接受手术治疗的5例脑瘫患儿胫骨骨膜标本（对照组）。首先观察标本的大体形态学特点;然后对组织切片进行苏木精-伊红染色, 描述组织形态学特点, 并计算平均血管密度;最后对组织切片进行CD34、蛋白基因产物9.5（protein gene product ...

Objective To compare the histopathological characteristics of periosteum between congenital pseudarthrosis of tibia (CPT)with neurofibromatosis type 1 (NF1)and CPT without NF1. Methods From September 2016 to December 2020, periosteal specimens of the lesions were collected from 20 children with CPT & NF1 (NF1-CPT group)and another 20 without CPT & NF1 (non-NF1-CPT group). And tibial periosteal specimens were harvested from five surgical children with cerebral palsy from December 2021 to January 2021 (control group). Gross morphological characte...