会议论文

Huang, Lei;Su, Qi

英文

2014 INTERNATIONAL CONFERENCE ON BIOLOGICAL ENGINEERING AND BIOMEDICAL (BEAB 2014)

2014

29-33

International Conference on Biological Engineering and Biomedical (BEAB)

JAN 10-12, 2014

Yichang, PEOPLES R CHINA

[Huang, Lei] Hunan Prov Hosp Tradit Chinese Med, Zhuzhou, Peoples R China.^[Chen, Xin] Hunan Tradit Chinese Med Coll, Zhuzhou, Peoples R China.^[Ouyang, Xinping;He, Pingping] Univ South China, Inst Cardiovascular Res, Dept Physiol, Coll Med, Hengyang, Peoples R China.^[He, Pingping] Univ South China, Sch Nursing, Hengyang, Peoples R China.^[Wang, Bo;Liao, Huiying] Univ South China, First Affiliated Hosp, Hengyang, Peoples R China.^[Lu, Suqing] Univ Guilin Med, Affiliated Hosp, Dept Urol, Guilin, Peoples R China.^[Su, Qi] Univ South China, Dept Pathol, Hengyang, Peoples R China.

Shanghai Jiaotong Univ, Nankai Univ

439 DUKE STREET, LANCASTER, PA 17602-4967 USA

DESTECH PUBLICATIONS, INC

978-1-60595-162-1

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81300158]; Hunan Provincial Science and Technology Department of China [2013FJ3027]; Human Province Education Department of China [13B103]; Hengyang Science and Technology Department of China [2013KS25, 2013KS20]

本校为通讯机构

In this study, we down-regulate the expression of calreticulin (CRT) in differentiation of human leukemic HL-60 cells induced by diallyl disulfide (DADS) so as to find out the molecular mechanism of differentiation in HL-60 cells induced by DADS. By using several methods like Giemsa's staining, siRNA, MTT, qPCR, Westenbloting, flow cytometry etc., we tested the morphology changes of HL-60 cells, detected the expression of CRT before and after the use of siRNA and DADS, also we measured the proliferation of HL-60 cells. The results showed that DADS can apparently change the morphology of HL-60,...