Enhanced Photodynamic Therapy by Improved Light Energy Capture Efficiency of Porphyrin Photosensitizers

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成果类型：

期刊论文

作者：

Tian, Zejie;Li, Hui;Liu, Zhenhua;Yang, Lingyan;Zhang, Chaoyang;...

通讯作者：

Liu, YM

作者机构：

[Liu, Yunmei; Yang, Lingyan; Li, Hui; Liu, YM; Liu, Zhenhua; Tian, Zejie] Univ South China, Inst Pharm & Pharmacol, Hunan Prov Cooperat Innovat Ctr Mol Target New Dru, 28 Changsheng Rd, Hengyang 421001, Hunan, Peoples R China.

[Liu, Yunmei; Yang, Lingyan; Li, Hui; Liu, YM; Liu, Zhenhua; Tian, Zejie] Hunan Prov Key Lab Tumor Microenvironm Respons Dru, Changsheng Rd, Hengyang 421001, Hunan, Peoples R China.

[He, Jun; Zhang, Chaoyang] Univ South China, Inst Chem & Chem Engn, Hengyang 421001, Hunan, Peoples R China.

[Ai, Wenbin] Univ South China, Affiliated Hosp 2, Hengyang 421001, Hunan, Peoples R China.

通讯机构：

[Liu, YM ] U

Univ South China, Inst Pharm & Pharmacol, Hunan Prov Cooperat Innovat Ctr Mol Target New Dru, 28 Changsheng Rd, Hengyang 421001, Hunan, Peoples R China.

Hunan Prov Key Lab Tumor Microenvironm Respons Dru, Changsheng Rd, Hengyang 421001, Hunan, Peoples R China.

语种：

英文

关键词：

Cancer;Photodynamic therapy;Photosensitizers;Porphyrin

期刊：

CURRENT TREATMENT OPTIONS IN ONCOLOGY

ISSN：

1527-2729

年：

2023

卷：

期：

页码：

1274-1292

DOI：

10.1007/s11864-023-01120-0

基金类别：

This work was supported by Hunan Province’s Students Innovation and Entrepreneurship Training Program (Xiangjiaotong [2022] 174–3149) and Scientific Research Program of Hunan Health Commission in 2019 (B2019113).

机构署名：

本校为第一且通讯机构

院系归属：

化学化工学院

药学与生物科学学院

摘要：

Photodynamic therapy (PDT) has garnered increasing attention in cancer treatment because of its advantages such as minimal invasiveness and selective destruction. With the development of PDT, impressive progress has been made in the preparation of photosensitizers, particularly porphyrin photosensitizers. However, the limited tissue penetration of the activating light wavelengths and relatively low light energy capture efficiency of porphyrin photosensitizers are two major disadvantages in conventional photosensitizers. Therefore, tissue penetr...

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Enhanced Photodynamic Therapy by Improved Light Energy Capture Efficiency of Porphyrin Photosensitizers

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