Chlamydia is a kind of obligate intracellular pathogen. Regulating host cell autophagy and apoptosis plays important roles in Chlamydia infection, hGBP1/2 and Irga6 are important molecules which regulate host cell autophagy in Chlamydia infection. Sev- eral signal pathways including Raf/MEK/ERK pathway and PI3K/Akt pathway can regulate host cell apoptosis induced by Chlamydia. The paper reviewed the important molecules and signal pathways which regulat...
