期刊论文

Tian, Ying

英文

Clinical Biochemistry

0009-9120

2013

46

9

733-739

10.1016/j.clinbiochem.2013.03.003

We acknowledge Hao Chen and Lan Ding for their help with lipid measurements; Xiaoou Wang, Wuzhe Chen, and Yongqiang Zhou for their help with the sample collects; and Xinhui Qiao, Li Tian and Mingde Fu for scientific discussions and mentorship. This work was supported by the grants from the Natural Science Foundation of China (Grant No. 30800474 ).

本校为第一且通讯机构

Aims: This study aims to examine the possible associations between high density lipoprotein (HDL) subclass distribution and APOA5-1131T>C polymorphism in hypertriglyceridemia. Methods: The distribution of HDL subclasses was quantified by 2-dimensional electrophoresis in conjunction with immunodetection method. The APOA5-1131T>C polymorphism was identified in 95 hypertriglyceridemic (HTG) patients and 102 healthy subjects by polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP). Results: The APOA5-1131C (C) allele frequency was higher in the HTG group than in the control...