CRediT authorship contribution statement Dan Qiu: Writing – review & editing, Data curation, Conceptualization. Lixia Li: Writing – review & editing. Xiaoqing Yu: Writing – review & editing, Visualization, Data curation. Zhenhua Xiao: Writing – review & editing, Supervision. Keqian Chen: Writing – review & editing, Supervision. Zongbao Wang: Supervision, acquisition. Shuzhi Wang: Supervision, acquisition, Conceptualization. This work was supported by the Natural Sciences Foundation of Hunan Province ( 2025JJ50664 ), the Scientific Research Project of Hunan Provincial Department of Education ( 23A0338 ), the Project of Hunan Provincial Health Committee ( D202302048902 ), and the College Student Innovation and Entrepreneurship Training Program of Hunan Province ( S202310555321 ), University of South China, China.