Molecular Programming of NIR-IIb-Emissive Semiconducting Small Molecules for In Vivo High-Contrast Bioimaging Beyond 1500 nm
作者:
Yuan, Yi;Feng, Zhe;Li, Shengliang;Huang, Zhongming;Wan, Yingpeng;...
期刊:
Advanced Materials ,2022年34(19):e2201263 ISSN:0935-9648
通讯作者:
Li, SL;Lee, CS;Qian, J
作者机构:
[Huang, Zhongming; Yuan, Yi; Li, Shengliang] Soochow Univ, Coll Pharmaceut Sci, Suzhou 215123, Peoples R China.;[Yuan, Yi; Lee, Chun-Sing; Cao, Chen] City Univ Hong Kong, Dept Chem, Ctr Super Diamond & Adv Films COSDAF, Kowloon, 83 Tat Chee Ave, Hong Kong 000000, Peoples R China.;[Qian, Jun; Wu, Lan; Feng, Zhe; Zhou, Jing; Qian, J] Zhejiang Univ, Int Res Ctr Adv Photon, Coll Opt Sci & Engn, State Key Lab Modern Opt Instrumentat,Ctr Opt & E, Hangzhou 310058, Peoples R China.;[Wan, Yingpeng] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.;[Lin, Sien] Chinese Univ Hong Kong, Li Ka Shing Inst Hlth Sci, Stem Cells & Regenerat Med Lab, Dept Orthopaed & Traumatol,Shatin, Hong Kong 000000, Peoples R China.
通讯机构:
[Lee, CS ] C;[Li, SL ] S;[Qian, J ] Z;Soochow Univ, Coll Pharmaceut Sci, Suzhou 215123, Peoples R China.;City Univ Hong Kong, Dept Chem, Ctr Super Diamond & Adv Films COSDAF, Kowloon, 83 Tat Chee Ave, Hong Kong 000000, Peoples R China.
关键词:
fluorescence imaging;molecular programming;nanoparticles;NIR-II;semiconducting oligomers
摘要:
Materials with long-wavelength second near-infrared (NIR-II) emission are highly desired for in vivo dynamic visualizating of microstructures in deep tissues. Herein, by employing an atom-programming strategy, a series of highly fluorescent semiconducting oligomers (SOMs) with tunable NIR-IIb emissions are developed for bioimaging applications. After self-assembly into nanoparticles (NPs), they show good brightness, high photostability, and satisfactory biocompatibility. The SOM NPs are applied as probes for high-resolution imaging of whole-body and hind-limb blood vessels, biliary tract, and bladder with their emissions over 1500nm. This work demonstrates an atom-programming strategy for constructing semiconducting small molecules with enhanced NIR-II fluorescence for deep-tissue imaging, affording new insight for advancing molecular design of NIR-II fluorophores. © 2022 Wiley-VCH GmbH.
语种:
英文
展开
Synthesis of Three Dimensional Cs-gamma-CD-MOFs and the Adsorption of Myricetin
作者:
Xie, Lan;Zheng, Yangyang;Deng, Jie;Jiang, Wenkang;Liu, Huijun
期刊:
Australian Journal of Chemistry ,2021年74(9):676-683 ISSN:0004-9425
通讯作者:
Liu, Huijun(liuhuijun@usc.edu.cn)
作者机构:
[Zheng, Yangyang; Liu, Huijun; Deng, Jie; Xie, Lan; Jiang, Wenkang] Univ South China, Dept Chem & Chem Engn, Hengyang 421001, Hunan, Peoples R China.;[Liu, Huijun; Xie, Lan] Univ South China, Hunan Key Lab Design & Applicat Actinide Complexe, Hengyang 421001, Hunan, Peoples R China.
关键词:
MOF;gamma-CD;Cs-gamma-CD-MOFs;adsorption;myricetin;molecular docking
摘要:
A new Cs-gamma-CD-MOF material obtained in colourless large crystals and with a three-dimensional porous structure containing coordinated by cesium ions and gamma-cyclodextrin was synthesised by an improved vapour diffusion method. The chemical formula of the Cs-gamma-CD-MOF material was C24H34CsO20, with the I-4 space group. Compared with the traditional solvent vapour diffusion method (7 days), this method is advantageous for rapid crystal formation (1 day). Simultaneously, the drug adsortion capacity of gamma-CD and Cs-gamma-CD-MOFs for myricetin was compared and the results indicated that Cs-gamma-CD-MOFs (280.05 mg g(-1)) have a higher drug adsorption capacity than gamma-CD (142.92 mg g(-1)). Finally, the energy and conformation of the Cs-gamma-CD-MOF material for adsorbing the drug myricetin were obtained through molecular docking.
语种:
英文
展开
Aryl acyl peroxides for visible-light induced decarboxylative arylation of quinoxalin-2(1: H)-ones under additive-, metal catalyst-, and external photosensitizer-free and ambient conditions
作者:
Xie, Long-Yong;Peng, Sha;Yang, Li-Hua;Peng, Cun;Lin, Ying-Wu;...
期刊:
Green Chemistry ,2021年23(1):374-378 ISSN:1463-9262
通讯作者:
He, Wei-Min
作者机构:
[Yang, Li-Hua; He, Wei-Min; Xie, Long-Yong; Peng, Sha; Peng, Cun] Hunan Univ Sci & Engn, Dept Chem & Bioengn, Yongzhou 425100, Peoples R China.;[Lin, Ying-Wu] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.;[Yu, Xianyong] Hunan Univ Sci & Technol, Sch Chem & Chem Engn, Xiangtan 411201, Peoples R China.;[Peng, Yu-Yu; Cao, Zhong] Changsha Univ Sci & Technol, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Changsha 410114, Peoples R China.
通讯机构:
[He, Wei-Min] H;Hunan Univ Sci & Engn, Dept Chem & Bioengn, Yongzhou 425100, Peoples R China.
摘要:
Aryl radicals were generated for the first time from cheap and easily available aryl acyl peroxides in eco-friendly ethyl acetate under ambient conditions and visible-light illumination in the absence of any additive, metal catalyst, or external photosensitizer. The present arylation of quinoxalin-2(1H)-ones was chemo- and regioselective, and provided good access to various 3-arylquinoxalin-2(1H)-ones. This journal is © The Royal Society of Chemistry.
语种:
英文
展开
Preparation of LiNi0·6Co0·2Mn0·2O2 by PVP modified liquid-phase assisted solid-phase method and its electrochemical energy storage performance
作者:
Yang Xiaoxiao;Yang Weitong;Peng Junqi;Lu Xiaoying;Jiang Qi;...
期刊:
Ceramics International ,2021年47(21):30266-30272 ISSN:0272-8842
通讯作者:
Qi, Jiang(jiangqi66@163.com);Xiaoying, Lu(luxy2005@swjtu.cn)
作者机构:
[Yang Xiaoxiao; Peng Junqi; Jiang Qi; Lu Xiaoying; Yang Weitong] Southwest Jiaotong Univ, Superconduct & New Energy R&D Ctr, Key Lab Magnet Suspens Technol & Maglev Vehicle, Minist Educ, Chengdu 610031, Peoples R China.;[Wang Guoping; Cao Fangcheng] Nanhua Univ, Sch Chem Engn, Hengyang 412001, Peoples R China.
通讯机构:
[Lu Xiaoying; Jiang Qi] K;Key Laboratory of Magnetic Suspension Technology and Maglev Vehicle (Ministry of Education), Superconductivity and New Energy R&D Center, Southwest Jiaotong University, Chengdu, 610031, China
关键词:
LiNi0.6Co0.2Mn0.2O2;Liquid-phase assisted solid-phase method;Polyvinylpyrrolidone modified;Electrochemical energy storage performance
摘要:
During the preparation process of LiNi0·6Co0·2Mn0·2O2 (NCM622) material via solid-phase method, the obtained NCM622 particle size is often inconsistent due to the inhomogeneous phase mixing, which makes the NCM622 material have low specific capacity and poor rate performance, and thus restrict the application of solid-phase method. In order to solve this problem and make full use of the advantages of solid-phase method, liquid-phase assisted mixing is used to replace the traditional mechanical mixing. At the same time, polyvinylpyrrolidone (PVP) is introduced to control the crystal morphology and particle size, thus a NCM622 material with excellent electrochemical energy storage performance has been prepared by the PVP modified liquid-phase assisted solid-state method in this paper. X-ray diffraction, scanning electron microscopy and Raman spectroscopy are used to characterize the morphology structure of the obtained materials. Their electrochemical energy storage performance is tested by program-controlled battery tester and electrochemical workstation after being assembled into button cells. The research results show that with the introduction of PVP, the particle size of the obtained material becomes smaller, the particle size distribution is more uniform, and the degree of cation mixing is further reduced. When the PVP adding amount is up to 1.6 wt %, the obtained material shows the best electrochemical performance: its first discharge specific capacity and coulomb efficiency are 183.19 mAh.g−1 and 88 % (0.1C), respectively. The capacity retention rate is 96.5 % after 100 cycles at 1C (half-cell system and laboratory conditions), which is comparable or better than those by other preparation methods, showing a good application prospect. © 2021 Elsevier Ltd and Techna Group S.r.l.
语种:
英文
展开
The Application Status of Nanoscale Cellulose-Based Hydrogels in Tissue Engineering and Regenerative Biomedicine
作者:
Wang, Chenyang;Bai, Jin;Tian, Pei;Xie, Rui;Duan, Zifan;...
期刊:
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY ,2021年9:732513 ISSN:2296-4185
通讯作者:
Xie, Rui(xierui1511@163.com);Tao, Yuqiang(taoyuqiang@usc.edu.cn)
作者机构:
[Wang, Chenyang; Bai, Jin; Tian, Pei; Xie, Rui; Duan, Zifan; Tao, Yuqiang] School of Chemistry and Chemical Engineering, University of South China, Hengyang, China;[Lv, Qinqin] The Fourth College of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, China
通讯机构:
[Xie, R.; Tao, Y.] S;School of Chemistry and Chemical Engineering, China
关键词:
nanoscale;Cellulose;Hydrogel;biomedicine;Non-toxic material
摘要:
As a renewable, biodegradable, and non-toxic material with moderate mechanical and thermal properties, nanocellulose-based hydrogels are receiving immense consideration for various biomedical applications. With the unique properties of excellent skeletal structure (hydrophilic functional groups) and micro-nano size (small size effect), nanocellulose can maintain the three-dimensional structure of the hydrogel to a large extent, providing mechanical strength while ensuring the moisture content. Owing to its unique features, nanocellulose-based hydrogels have made excellent progress in research and development on tissue engineering, drug carriers, wound dressings, development of synthetic organs, 3D printing, and biosensing. This review provides an overview of the synthesis of different types of nanocellulose, including cellulose nanocrystals, cellulose nanofibers, and bacterial nanocellulose, and describes their unique features. It further provides an updated knowledge of the development of nanocellulose-based functional biomaterials for various biomedical applications. Finally, it discusses the future perspective of nanocellulose-based research for its advanced biomedical applications. Copyright © 2021 Wang, Bai, Tian, Xie, Duan, Lv and Tao.
语种:
英文
展开
Dual-signal amplification electrochemical sensing for the sensitive detection of uranyl ion based on gold nanoparticles and hybridization chain reaction-assisted synthesis of silver nanoclusters
作者:
Chen, Lei;Liu, Jinquan;Cao, Chen;Tang, Shuangyang;Lv, Changyin;...
期刊:
Analytica Chimica Acta ,2021年1184:338986 ISSN:0003-2670
通讯作者:
Li, Le
作者机构:
[Yang, Shengyuan; Liu, Ling; Liu, Jinquan; Li, Le; Chen, Lei; Lv, Changyin; Xiao, Xilin; Sun, Lin; Zhu, Bingyu] Univ South China, Hengyang Med Sch, Coll Publ Hlth, Hengyang 421001, Hunan, Peoples R China.;[Yang, Shengyuan; Liu, Ling; Liu, Jinquan; Li, Le; Chen, Lei; Lv, Changyin; Xiao, Xilin; Sun, Lin; Zhu, Bingyu] Hunan Prov Key Lab Typ Environm Pollut & Hlth Haz, Hengyang 421001, Hunan, Peoples R China.;[Yang, Shengyuan; Liu, Ling; Liu, Jinquan; Li, Le; Chen, Lei; Lv, Changyin; Xiao, Xilin; Sun, Lin; Zhu, Bingyu] Univ South China, Key Lab Hlth Hazard Factors Inspect & Quarantine, Hengyang 421001, Hunan, Peoples R China.;[Cao, Chen] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Hunan, Peoples R China.;[Tang, Shuangyang] Univ South China, Inst Pathogen Biol, Hengyang 421001, Hunan, Peoples R China.
通讯机构:
[Li, Le] U;Univ South China, Hengyang Med Sch, Coll Publ Hlth, Hengyang 421001, Hunan, Peoples R China.
关键词:
Electrochemical sensing;Gold nanoparticles (AuNPs);Hybrid chain reaction (HCR);Silver nanoclusters (AgNCs);Uranyl ions (UO(2)(2+))
摘要:
Herein, a dual-signal amplification electrochemical sensing has been proposed for the ultrasensitive detection of uranyl ions (UO22+) by integration of gold nanoparticles (AuNPs) and hybridization chain reaction (HCR)-assisted synthesis of silver nanoclusters (AgNCs). In this sensing platform, AuNPs are used as an ideal signal amplification carrier, aiming at increasing the loads of UO22+-specific DNAzyme on the gold electrode. In the presence of UO22+, UO22+-specific DNAzyme can be activated, leading to the cleavage of substrate strands (S-DNA). Then, HCR is triggered to produce long dsDNA through hybridization the probe with the ssDNA on the electrode surface. As a result, an amplified electrochemical response can be detected by inserting a large amount of AgNCs generated in situ using dsDNA as template. Featured with amplification efficiency, good specificity and high sensitivity, the strategy could quantitatively detect UO22+ down to 6.2 pM with a linear calibration range from 20 pM to 5000 pM. The proposed sensing platform has been also successfully demonstrated the practical application of detecting UO22+, indicating that the developed method has the potential applications and can open up a new avenue for highly sensitive detection of UO22+ in environmental monitoring. © 2021 Elsevier B.V.
语种:
英文
展开
Revisiting imidazolium receptors for the recognition of anions: Highlighted research during 2010-2019
作者:
Hu, Ying;Long, Shuangshuang;Fu, Haiyan;She, Yuanbin* ;Xu, Zhaochao* ;...
期刊:
CHEMICAL SOCIETY REVIEWS ,2021年50(1):589-618 ISSN:0306-0012
通讯作者:
She, Yuanbin;Yoon, Juyoung;Xu, Zhaochao
作者机构:
[Hu, Ying; She, Yuanbin] Zhejiang Univ Technol, Coll Chem Engn, Hangzhou 310014, Zhejiang, Peoples R China.;[Yoon, Juyoung; Hu, Ying] Ewha Womans Univ, Dept Chem & Nanosci, Seoul 120750, South Korea.;[Xu, Zhaochao; Long, Shuangshuang] Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China.;[Long, Shuangshuang] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.;[Fu, Haiyan] South Cent Univ Nationalities, Sch Pharmaceut Sci, Modernizat Engn Technol Res Ctr Ethn Minor Med Hu, Wuhan 430074, Peoples R China.
通讯机构:
[She, Yuanbin] Z;[Yoon, Juyoung] E;[Xu, Zhaochao] C;Zhejiang Univ Technol, Coll Chem Engn, Hangzhou 310014, Zhejiang, Peoples R China.;Ewha Womans Univ, Dept Chem & Nanosci, Seoul 120750, South Korea.
摘要:
Imidazolium based receptors selectively recognize anions, and have received more and more attention. In 2006 and 2010, we reviewed the mechanism and progress of imidazolium salt recognition of anions, respectively. In the past ten years, new developments have emerged in this area, including some new imidazolium motifs and the identification of a wider variety of biological anions. In this review, we discuss the progress of imidazolium receptors for the recognition of anions in the period of 2010-2019 and highlight the trends in this area. We first classify receptors based on motifs, including some newly emerging receptors, as well as new advances in existing receptor types at this stage. Then we discuss separately according to the types of anions, including ATP, GTP, DNA and RNA. This journal is © The Royal Society of Chemistry.
语种:
英文
展开
Effects of reduction method on reduced graphene oxide and its electrochemical energy storage performance
作者:
Chen Bing;Yu Jiahao;Lu Xiaoying;Jiang Qi;Wang Guoping;...
期刊:
Diamond and Related Materials ,2021年114:108305 ISSN:0925-9635
通讯作者:
Xiaoying, Lu(luxy2005@swjtu.cn)
作者机构:
[Chen Bing; Jiang Qi; Lu Xiaoying; Yu Jiahao] Southwest Jiaotong Univ, Superconduct & New Energy R&D Ctr, Key Lab Adv Technol Mat, Minist Educ China, Chengdu 610031, Peoples R China.;[Jin Linghua; Wang Guoping] Nanhua Univ, Sch Chem Engn, Hengyang 412001, Peoples R China.
通讯机构:
[Lu Xiaoying; Jiang Qi] K;Key Laboratory of Advanced Technologies of Materials (Ministry of Education of China), Superconductivity and New Energy R&D Centre, Southwest Jiaotong University, Chengdu 610031, China
关键词:
Electrochemical energy storage performance;Morphology structure;Reduced graphene oxide;Reduction method
摘要:
To enhance the application of reduced graphene oxide (rGO) in energy storage field, the effects of reduction method on rGO and its electrochemical energy storage performance were researched in this paper. Green and environmentally friendly reduction methods, such as L-ascorbic acid method (LAA), hydrothermal method and sodium borohydride method (NaBH4), were used to reduce the GO obtained by Hummers' method to rGO. The obtained samples were analyzed and characterized by Fourier transform Infrared spectroscopy, Ultraviolet-visible spectroscopy, X-ray diffraction, scanning electron microscope, Raman spectroscopy and N2 absorption and desorption. The obtained rGO samples were being assembled into symmetrical electrochemical super-capacitors with using organic solution as the electrolyte to characterize their electrochemical energy storage performance including cyclic voltammetry, galvanostatic charge and discharge, AC impedance and cycle life tests. The research results showed that the GO could all be changed into rGO via the reduction methods mentioned above, but the reduction degree and morphology structure of the obtained rGOs were quite different: the rGO obtained by LAA had a very smooth surface; the surface of rGO obtained by hydrothermal reduction method had wrinkles and formed a layered cross-linked structure; while the rGO obtained by NaBH4 showed severe agglomeration, forming obvious blocks. The electrochemical test results showed that the rGO obtained by hydrothermal reduction had the best electrochemical performance among the samples: its specific capacitance could reach 140 F g−1 (organic electrolyte) at a current density of 1 A g−1, moreover it had an energy density of 43.75 Wh kg−1 and a power density of 4500 W kg−1. © 2021 Elsevier B.V.
语种:
英文
展开
Asymmetric polysaccharide-bound graphene electrode configuration with enhanced electrosorption performance for uranium (VI) ions
作者:
Liao, Yun;Yan, Chuan;Zeng, Ke;Liao, Chenglin;Wang, Meng
期刊:
Chemical Engineering Journal ,2021年424:130351 ISSN:1385-8947
通讯作者:
Wang, Meng(wmeng020321@163.com)
作者机构:
[Zeng, Ke; Liao, Yun] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Hunan, Peoples R China.;[Zeng, Ke; Liao, Yun] Univ South China, Hunan Key Lab Design & Applicat Actinide Complexe, Hengyang 421001, Hunan, Peoples R China.;[Yan, Chuan; Wang, Meng; Liao, Chenglin] Univ South China, Sch Nucl Sci & Technol, Hengyang 421001, Hunan, Peoples R China.
通讯机构:
[Meng Wang] S;School of Nuclear Science and Technology, University of South China, Hengyang, Hunan 421001, PR China
关键词:
Co-ions expusion;Electrosorption;Graphene;Polysaccharide binders;Uranium (VI)
摘要:
As an energy-saving and facile technology, the potential of capacitive deionization (CDI) starts to surface in enrichment and recovery of uranium (U(VI)) from aqueous solutions. However, co-ion expulsion effect and poor surface wettability of electrode materials limit the eletrosorption performance. Here, polysaccharides xanthan gum (XG)- and chitosan (CS) -bound porous reduced graphene (RGH) electrodes were rationally designed, and then assembled into asymmetrical electrode configuration for U(VI) eletrosorption. Owing to the introduction of polysaccharide binders, the oppositely charged groups on the surface of cathode and anode weaken the co-ions exclusion effect as well as endow their superior surface hydrophilicity and electroconductivity, which facilitates the electrosorption for U(VI). Meanwhile, the negatively charged carboxylate groups could act as extra micro electric fields to attract U(VI) cations, and form stronge complexation between them. As a consequence, asymmetrical polysaccharide-bound RGH configuration gave rise to a larger removal ratio of 97.9% within 4 h at 1.2 V, as well as 2.5 times faster kinetics than symmetrical PVDF-bound RGH electrode configuration. Moreover, the accumulated adsorption capacity in six adsorption–desorption cycles of the former is up to 1413.0 mg g−1, 75% higher than the latter, which is of practical significance and economic benefit for electrosorption application. © 2021 Elsevier B.V.
语种:
英文
展开
In vitro measurement of superoxide dismutase-like nanozyme activity: a comparative study
作者:
Liu, Yufeng;Zhang, Yihong;Liu, Quanyi;Wang, Quan;Lin, Anqi;...
期刊:
ANALYST ,2021年146(6):1872-1879 ISSN:0003-2654
通讯作者:
Wei, Hui
作者机构:
[Liu, Yufeng; Wei, Hui; Lin, Anqi; Zhang, Yihong; Wang, Quan] Nanjing Univ, Coll Engn & Appl Sci, Dept Biomed Engn, Nanjing 210023, Jiangsu, Peoples R China.;[Liu, Quanyi; Du, Yan] Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Electroanalyt Chem, Changchun 130022, Jilin, Peoples R China.;[Luo, Jie; Lin, Ying-Wu] Univ South China, Lab Prot Struct & Anct, Sch Chem & Chem Engn, Hengyang 421001, Hunan, Peoples R China.;[Wei, Hui] Nanjing Univ, Nanjing Natl Lab Microstruct, Jiangsu Key Lab Artificial Funct Mat, Nanjing 210093, Jiangsu, Peoples R China.;[Wei, Hui] Nanjing Univ, State Key Lab Analyt Chem Life Sci, Sch Chem & Chem Engn, Chem & Biomed Innovat Ctr ChemBIC, Nanjing 210023, Jiangsu, Peoples R China.
通讯机构:
[Wei, Hui] N;Nanjing Univ, Coll Engn & Appl Sci, Dept Biomed Engn, Nanjing 210023, Jiangsu, Peoples R China.;Nanjing Univ, Nanjing Natl Lab Microstruct, Jiangsu Key Lab Artificial Funct Mat, Nanjing 210093, Jiangsu, Peoples R China.;Nanjing Univ, State Key Lab Analyt Chem Life Sci, Sch Chem & Chem Engn, Chem & Biomed Innovat Ctr ChemBIC, Nanjing 210023, Jiangsu, Peoples R China.
关键词:
measurement;superoxide;dismutase-like
摘要:
Analyzing the SOD-like activity of nanozymes in vitro is of great importance for identifying new nanozymes and predicting their potential biological effects in vivo. However, false negative or positive results occasionally occur due to the mismatch between the detection methods and nanozymes. Here, five typical SOD-like nanozymes, including CeO2, Mn3O4, Prussian blue (PB), PCN222-Mn, and Pt NPs, have been used to evaluate the sensitivity and accuracy of several commonly used in vitro detection methods. By systematically analyzing the detection results, several precautions have been taken. (1) The hydroethidine (HE) probe could be disturbed by the nanozyme with oxidative ability. (2) The nitro blue tetrazolium (NBT) probe has a moderate sensitivity due to the poor water solubility of its reduced product. (3) The water-soluble tetrazolium salt (WST)-8 probe has a higher sensitivity than both NBT and iodonitrotetrazolium chloride (INT). (4) The detection system using the irradiation of riboflavin to produce O2- might be interfered by the nanozyme with photosensibility. (5) Both the quality of DMPO and incubation time are important factors for electron paramagnetic resonance (EPR) measurement. This study will be useful for choosing more suitable in vitro detection methods of SOD-like activity for nanozymes in the future. This journal is © The Royal Society of Chemistry.
语种:
英文
展开
光/电催化喹喔啉酮官能团化反应研究进展
作者:
Sun, Kai;Xiao, Fang;Yu, Bing;He, Wei-Min
期刊:
催化学报 ,2021年42(11):1921-1943 ISSN:0253-9837
通讯作者:
Yu, Bing(bingyu@zzu.edu.cn);He, Wei-Min(weiminhe2016@yeah.net)
作者机构:
[Sun, Kai; Xiao, Fang; Yu, Bing] Zhengzhou Univ, Coll Chem, Green Catalysis Ctr, Zhengzhou 450001, Henan, Peoples R China.;[Xiao, Fang] Cent South Univ, Xiangya Sch Publ Hlth, Changsha 410078, Hunan, Peoples R China.;[He, Wei-Min] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Hunan, Peoples R China.
通讯机构:
[Yu, B.] G;[He, W.-M.] S;Green Catalysis Center, China;School of Chemistry and Chemical Engineering, China
关键词:
C–H functionalization;Electrocatalysis;Photocatalysis;Quinoxalin-2(1H)-ones
摘要:
The photo-/electrocatalytic functionalization of quinoxalin-2(1H)-ones has emerged as a promising and powerful approach for post-synthetic modification of quinoxalin-2(1H)-ones. This review provides an overview of recent developments in photo-/electrocatalytic functionalization of quinoxalin-2(1H)-ones including arylation, alkylation, fluoroalkylation, amination, phosphorylation, acylation, alkoxylation, thiolation, silylation, and annulation. The reaction scope and the related mechanism are also well discussed. © 2021 Dalian Institute of Chemical Physics, the Chinese Academy of Sciences
语种:
英文
展开
Recent advancements in metal-organic frameworks for green applications
作者:
Duan, Chongxiong;Yu, Yi;Xiao, Jing;Li, Yuanyuan;Yang, Pengfei;...
期刊:
绿色能源与环境(英文) ,2021年6(1):33-49 ISSN:2096-2797
通讯作者:
Hu, Fei(mfhufei@126.com)
作者机构:
[Li, Yuanyuan; Duan, Chongxiong; Hu, Fei] Foshan Univ, Sch Mat Sci & Hydrogen Engn, Foshan 528231, Peoples R China.;[Yu, Yi; Xi, Hongxia; Xiao, Jing] South China Univ Technol, Sch Chem & Chem Engn, Guangzhou 510640, Peoples R China.;[Yang, Pengfei] Univ South China, Sch Chem & Chem Engn, Changsha 421001, Hunan, Peoples R China.
通讯机构:
[Fei Hu; Hongxia Xi] S;School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, 510640, China<&wdkj&>School of Materials Science and Hydrogen Engineering, Foshan University, Foshan, 528231, China
关键词:
Metal-organic frameworks;Environmental and energy issues;Industrial production;Green applications
摘要:
A series of environmental and energy issues, such as global warming, water pollution, acid rain, and energy shortage, have to be settled urgently. Metal–organic frameworks (MOFs) are compounds consisting of metal ions or clusters coordinated to organic ligands, which show great promise for alleviating or mitigating these challenges owing to their outstanding physical and chemical properties. In this review, we summarize the recent advances of MOFs in the fields of green applications, including carbon capture, harmful gas removal, sewage treatment, and green energy storage. In addition, the challenges and prospects of the large-scale commercialized use of MOFs in handling environmental issues are also discussed. © 2021 Institute of Process Engineering, Chinese Academy of Sciences
语种:
英文
展开
Spider Toxin Peptide-Induced NIR Gold Nanocluster Fabrication for GSH-Responsive Cancer Cell Imaging and Nuclei Translocation
作者:
Tan, Huaxin;Liu, Sisi;He, Yaolin;Cheng, Guofeng;Zhang, Yu;...
期刊:
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY ,2021年9:780223 ISSN:2296-4185
通讯作者:
Hu, Lidan
作者机构:
[Tan, Huaxin; Hu, Lidan; Zhang, Yu; Cheng, Guofeng] Univ South China, Key Lab Ecol Environm & Crit Human Dis Prevent Hu, Dept Biochem & Mol Biol, Dept Educ,Sch Basic Med,Hengyang Med Sch, Hengyang, Peoples R China.;[Liu, Sisi] Univ South China, Sch Publ Hlth, Hengyang Med Sch, Hengyang, Peoples R China.;[He, Yaolin] Univ South China, Affiliated Hosp 2, Hengyang Med Sch, Dept Radiotherapy, Hengyang, Peoples R China.;[Wei, Xiaojie] Univ South China, Sch Pharm, Hengyang Med Sch, Hengyang, Peoples R China.
通讯机构:
[Hu, Lidan] U;Univ South China, Key Lab Ecol Environm & Crit Human Dis Prevent Hu, Dept Biochem & Mol Biol, Dept Educ,Sch Basic Med,Hengyang Med Sch, Hengyang, Peoples R China.
关键词:
NIR gold nanoclusters;spider toxin peptide;Cancer cell imaging;nuclei translocation;GSH-responsive
摘要:
Goldnanoclusters (GNCs) have become a promising nanomaterial for bioimaging because of their unique optical properties and biocompatibility. In this study, lycosin-I peptide, which possesses a highly selective anticancer activity by affecting the permeability of cancer cell membrane, was firstly modified for constructing fluorescent GNCs (LGNCs) for bioimaging of tumor cells. The obtained LGNCs exhibited strong near-infrared (NIR) fluorescence, which can be further enhanced by the peptide-induced aggregation and selectively stained three cancerous cell lines over normal cell lines with low intrinsic toxicity. After uptake by tumor cells, LGNC aggregates can be depolymerized into ultrasmall nanoclusters by high-level glutathione (GSH) and realize the nuclear targeting translocation. Collectively, our work suggests the potential of natural active biomolecules in designing NIR fluorescent GNCs for bioimaging. Copyright © 2021 Tan, Liu, He, Cheng, Zhang, Wei and Hu.
语种:
英文
展开
Insights into complexation and enantioselectivity of uranyl-2-(2-hydroxy-3-methoxyphenyl)-9-(2-hydroxyphenyl)thiopyrano[3,2-h]thiochromene-4,7-dione with R/S-organophosphorus pesticides
作者:
Yang, Rong;Xiao, Yang;Tao, Xue-bing;Ma, Ming-jie;Wu, Zhi-lin;...
期刊:
Applied Organometallic Chemistry ,2021年35(9):e6331- ISSN:0268-2605
通讯作者:
Nie, Chang-ming(changmingnie@usc.edu.cn)
作者机构:
[Liao, Li-fu; Yang, Rong; Ma, Ming-jie; Wu, Zhi-lin; Xiao, Xi-lin; Xiao, Yang; Nie, Chang-ming; Tao, Xue-bing] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.;[Liao, Li-fu; Yang, Rong; Ma, Ming-jie; Wu, Zhi-lin; Xiao, Xi-lin; Xiao, Yang; Nie, Chang-ming; Tao, Xue-bing] Univ South China, Key Lab Hunan Prov Design & Applicat Nat Actinide, Hengyang, Peoples R China.
通讯机构:
[Chang-ming Nie] S;School of Chemistry and Chemical Engineering, University of South China, Hengyang, China<&wdkj&>Key Laboratory of Hunan Province for Design and Application of Natural Actinide Complexes, University of South China, Hengyang, China
关键词:
chiral organophosphorus pesticides;coordination;density functional theory (DFT);enantioselectivity recognition;Uranyl-HTTDN
摘要:
In order to explore the enantioselectivity of new uranyl receptors to chiral organophosphorus pesticides (COPs), we designed a novel ligand: 2-(2-hydroxy-3-methoxyphenyl)-9-(2-hydroxyphenyl)thiopyrano[3,2-h]thiochromene-4,7-dione (HTTDN) and constructed a new receptor of Uranyl-HTTDN by complexation of HTTDN with uranyl. The complexation and enantioselectivity of Uranyl-HTTDN to COPs of R/S-methamidophos (R/S-MAPs) and R/S-acephates (R/S-APs) were studied using density functional theory (DFT) method in this paper. The results showed that in vacuum and toluene, Uranyl-HTTDN could effectively recognize R/S-MAPs by complexation with oxygen of phosphoryl of methamidophos, with enatioselectivity coefficients of 91.80% and 86.74%, respectively. In vacuum, water, and acetone, Uranyl-HTTDN could also effectively identify R/S-APs by the oxygen of phosphoryl coordinating with U, and enatioselectivity coefficients toward R/S-APs were 99.41%, 91.09%, and 93.84%, respectively. These results could provide valuable information and theoretical reference for the further experiments of COPs separation. © 2021 John Wiley & Sons, Ltd.
语种:
英文
展开
The graceful art, significant function and wide application behavior of ultrasound research and understanding in carbamazepine (CBZ) enhanced removal and degradation by Fe0/PDS/US
作者:
Wei, Wei;Zhou, Dong;Feng, Li;Li, Xuhao;Hu, Lijun;...
期刊:
Chemosphere ,2021年278:130368 ISSN:0045-6535
通讯作者:
Feng, Li(fl19860314@126.com)
作者机构:
[Wei, Wei; Zhou, Dong] Anhui Jianzhu Univ, Sch Environm & Energy Engn, Hefei 230601, Peoples R China.;[Wei, Wei; Zhou, Dong] Anhui Prov Key Lab Environm Pollut Control & Reso, Hefei 230061, Peoples R China.;[Wei, Wei; Zhou, Dong] Key Lab Water Pollut Control & Wastewater Reuse A, Hefei 230061, Peoples R China.;[Li, Xuhao; Feng, Li; Wang, Yinli] Guangdong Univ Technol, Sch Civil & Transportat Engn, Guangzhou 510006, Guangdong, Peoples R China.;[Hu, Lijun] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Hunan, Peoples R China.
通讯机构:
[Li Feng] S;School of Civil and Transportation Engineering, Guangdong University of Technology, Guangzhou, 510006, Guangdong, China
关键词:
Active radicals;Carbamazepine removal;Potassium persulfate;Ultrasound;Zerovalent iron;pH
摘要:
Carbamazepine (CBZ) antibiotic organic contamination wastewater poses a huge threat to environmental safety. An advanced oxidation technology (Fe0/PDS/US) of using ultrasound (US) enhanced zero-valent iron/potassium persulfate (Fe0/PDS) can remove CBZ effectively. The optimal reaction conditions were determined by exploring the effect of single-factor experimental conditions such as ultrasonic power, ultrasonic frequency, CBZ concentration, solution pH, PDS dosage, and Fe0 dosage on the removal of CBZ. In addition, we also investigated into the effect of background ions (PO43−, HCO3−, Cl− and HA) on Fe0/PDS/US and analyzed the related results. The mechanism of CBZ removal in Fe0/PDS/US were explored by analyzing CBZ removal efficiency and reaction rates, the ion concentration of S2O82−, SO42−, Fe2+ and Fe3+, pH and the active radicals. The result indicates that US can improve the efficiency of activated PDS and expand the pH range of Fe0/PDS. It has prominent performance in catalytically degrading CBZ when the pH is 10.0. SO4•-, •OH and O2•- all coexist in the Fe0/PDS/US and make contribution to CBZ removal, whereas the SO4•− plays a key role. US can greatly promotes the degradation of target pollutant CBZ by speeding up the dissolution of the outer portion of iron powder, producing sufficient amount of Fe2+ with a continuous and stable way, and better activating S2O82− to generate sufficient SO4•− radicals. The degradation of CBZ may embrace three reaction processes, in which organic intermediate products with low molecular weight and biological toxicity is produced, boosting further mineralization and biodegradation of products. The Fe0/PDS/US is of great potential application value in removal of organic pollution and environmental purification. © 2021 Elsevier Ltd
语种:
英文
展开
Nanomessenger-Mediated Signaling Cascade for Antitumor Immunotherapy
作者:
Zhao, Henan;Wang, Liqiang;Zeng, Ke;Li, Jianghua;Chen, Wansong;...
期刊:
ACS Nano ,2021年15(8):13188-13199 ISSN:1936-0851
通讯作者:
Chen, Wansong(liuyounian@csu.edu.cn);Liu, You-Nian(chenws@csu.edu.cn)
作者机构:
[Chen, Wansong; Liu, You-Nian; Li, Jianghua; Zhao, Henan] Cent South Univ, Coll Chem & Chem Engn, Hunan Prov Key Lab Micro & Nano Mat Interface Sci, Changsha 410083, Hunan, Peoples R China.;[Wang, Liqiang] Zhengzhou Univ, Sch Mat Sci & Engn, Henan Prov Ind Technol Res Inst Resources & Mat, Zhengzhou 450001, Henan, Peoples R China.;[Zeng, Ke] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.
通讯机构:
[Wansong Chen; You-Nian Liu] H;Hunan Provincial Key Laboratory of Micro & Nano Materials Interface Science, College of Chemistry and Chemical Engineering, Central South University, Changsha, Hunan 410083, People’s Republic of China
关键词:
chemical messenger;signal cascade;messenger amplifier;Ca2+-dependent cell death;antitumor immunotherapy
摘要:
Chemical messengers have been recognized as signaling molecules involved in regulating various physiological and metabolic activities. Nevertheless, they usually show limited regulatory efficiency due to the complexity of biological processes. Especially for tumor cells, antideath pathways and tumor metastasis are readily activated to resist chemical messenger regulation, further impairing antitumor outcomes. Therefore, it is imperative to develop strategies for tumor eradication with chemical messengers. Herein, a nanomessenger was prepared with signaling transduction cascades to amplify the regulatory activity of chemical messengers and mediate antitumor immunotherapy. Ca2+ and H2S as two chemical messengers were released from nanomessengers to synergistically elevate intracellular Ca2+ stress and mediate subsequent cell death. Meanwhile, zinc protoporphyrin (ZnPP) as a messenger amplifier suppressed the antideath effect of tumor cells. As a result, tumor cells underwent Ca2+-dependent cell death via signaling transduction cascades to release tumor-associated antigens, which further served as an in situ tumor vaccine to activate antitumor immunity. In vivo studies revealed that both primary tumors and distant metastases were markedly eradicated. Furthermore, immunological memory was fabricated to arrest tumor metastasis and recurrence. This work introduces cascade engineering into chemical messengers and thus offers a strategy for amplifying chemical messenger-mediated cellular regulation, which would promote the future development of chemical messenger-mediated immunotherapy.` © 2021 American Chemical Society.
语种:
英文
展开
Folic Acid-Targeted MXene Nanoparticles for Doxorubicin Loaded Drug Delivery
作者:
Zhen Liu;Lan Xie;Jia Yan;Pengfei Liu;Huixiang Wen;...
期刊:
Australian Journal of Chemistry ,2021年74(12):847-855 ISSN:0004-9425
通讯作者:
Liu, Huijun(liuhuijun@usc.edu.cn)
作者机构:
[Zhen Liu; Lan Xie; Jia Yan; Huijun Liu] Department of Chemistry and Chemical Engineering, University of South China, Hunan, Hengyang;421001, China;[Pengfei Liu; Huixiang Wen] Hunan Key Laboratory for the Design and Application of Actinide Complexes, University of South China, Hunan, Hengyang;[Zhen Liu; Huijun Liu] 421001, China<&wdkj&>Hunan Key Laboratory for the Design and Application of Actinide Complexes, University of South China, Hunan, Hengyang;[Zhen Liu; Lan Xie; Jia Yan; Pengfei Liu; Huixiang Wen; Huijun Liu] 421001, China
关键词:
MXenes, targeted drug carrier, folate receptors, nanoparticles, doxorubicin, pH-responsive mechanism, cancer therapy.
摘要:
MXenes are two-dimensional (2D) materials with a large specific surface area and abundant surface functional groups. A folate receptors-targeted drug carrier was constructed based on the rich surface functional groups and high biocompatibility of MXenes. This drug carrier possesses as high as 69.9 % drug-loading capability and as long as 48 h drug release time. Tumour targeting and a pH-responsive mechanism can make MXene nanoparticles quickly accumulate in tumour sites and slowly release loads. The results showed that DOX was released in a large amount in a PBS solution at pH 4.5. Compared with the naked drug, MXenes-FA-SP@DOX has a higher cell inhibition rate and a longer drug action time at a lower concentration (less than 10 μg mg). This drug delivery system exhibited potential applications for the treatment of malignant tumour and this work extends the biomedical applications of MXenes in nanomedicine. © 2021 CSIRO.
语种:
英文
展开
Four-component synthesis of 3-aminomethylated imidazoheterocycles in EtOH under catalyst-free, oxidant-free and mild conditions
作者:
Gui, Qing-Wen;Wang, Bin-Bin;Zhu, Sha;Li, Fu-Long;Zhu, Meng-Xue;...
期刊:
Green Chemistry ,2021年23(12):4430-4434 ISSN:1463-9262
通讯作者:
He, Wei-Min(weiminhe2016@yeah.net)
作者机构:
[Zhu, Meng-Xue; Zhu, Sha; Gui, Qing-Wen; Wang, Bin-Bin; Yi, Min; Yu, Jia-Ling; Li, Fu-Long] Hunan Agr Univ, Coll Chem & Mat Sci, Changsha 410128, Peoples R China.;[Wu, Zhi-Lin; He, Wei-Min] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.
通讯机构:
[He, W.-M.] S;School of Chemistry and Chemical Engineering, China
摘要:
With green ethanol as the sole solvent, various 3-aminomethylated imidazoheterocycles were efficiently synthesized in one step through a four-component reaction of equimolar cheap and commercially available reactants at ambient temperature under metal-free, oxidant-free and mild conditions. © The Royal Society of Chemistry 2021.
语种:
英文
展开
Biotransformation of Lignin by an Artificial Heme Enzyme Designed in Myoglobin With a Covalently Linked Heme Group
作者:
Guo, Wen-Jie;Xu, Jia-Kun;Liu, Jing-Jing;Lang, Jia-Jia;Gao, Shu-Qin;...
期刊:
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY ,2021年9:664388 ISSN:2296-4185
通讯作者:
Lin, Ying-Wu(ywlin@usc.edu.cn);Xu, Jia-Kun(xujk@ysfri.ac.cn)
作者机构:
[Guo, Wen-Jie; Liu, Jing-Jing; Lin, Ying-Wu] Univ South China, Sch Chem & Chem Engn, Hengyang, Peoples R China.;[Xu, Jia-Kun] Chinese Acad Fishery Sci, Key Lab Sustainable Dev Polar Fisheries, Minist Agr & Rural Affairs,Pilot Natl Lab Marine, Yellow Sea Fisheries Res Inst,Lab Marine Drugs &, Qingdao, Peoples R China.;[Gao, Shu-Qin; Wen, Ge-Bo; Lang, Jia-Jia; Lin, Ying-Wu] Univ South China, Lab Prot Struct & Funct, Hengyang, Peoples R China.
通讯机构:
[Lin, Y.-W.] S;[Xu, J.-K.] K;Key Lab of Sustainable Development of Polar Fisheries, China;School of Chemistry and Chemical Engineering, China
关键词:
Protein design;Heme protein;artificial enzyme;Lignin;degradation
摘要:
The conversion of Kraft lignin in plant biomass into renewable chemicals, aiming at harvesting aromatic compounds, is a challenge process in biorefinery. Comparing to the traditional chemical methods, enzymatic catalysis provides a gentle way for the degradation of lignin. Alternative to natural enzymes, artificial enzymes have been received much attention for potential applications. We herein achieved the biodegradation of Kraft lignin using an artificial peroxidase rationally designed in myoglobin (Mb), F43Y/T67R Mb, with a covalently linked heme cofactor. The artificial enzyme of F43Y/T67R Mb has improved catalytic efficiencies at mild acidic pH for phenolic and aromatic amine substrates, including Kraft lignin and the model lignin dimer guaiacylglycerol-β-guaiacyl ether (GGE). We proposed a possible catalytic mechanism for the biotransformation of lignin catalyzed by the enzyme, based on the results of kinetic UV-Vis studies and UPLC-ESI-MS analysis, as well as molecular modeling studies. With the advantages of F43Y/T67R Mb, such as the high-yield by overexpression in E. coli cells and the enhanced protein stability, this study suggests that the artificial enzyme has potential applications in the biodegradation of lignin to provide sustainable bioresource. © Copyright © 2021 Guo, Xu, Liu, Lang, Gao, Wen and Lin.
语种:
英文
展开
Mechanism of recombinant bacteria adsorb UO22+ under culture condition
作者:
Shu, Yangzhen;Li, Shanshan;Xie, Jingxi;Guo, Kexin;Cheng, Conghui;...
期刊:
Enzyme and Microbial Technology ,2021年151:109920 ISSN:0141-0229
通讯作者:
Peng, Guowen(pgwnh78@163.com);Xiao, Fangzhu(xfzhunh@163.com)
作者机构:
[Shu, Yangzhen; Peng, Guowen] Univ South China, Sch Environm Protect & Safety Engn, Hengyang 421001, Hunan, Peoples R China.;[Xiao, Fangzhu; Cheng, Conghui; Guo, Kexin; Chen, Luoyao; Li, Shanshan] Univ South China, Sch Publ Hlth, Hengyang 421001, Hunan, Peoples R China.;[Xie, Jingxi; Peng, Guowen] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Hunan, Peoples R China.
通讯机构:
[Peng, G.; Xiao, F.] S;School of Environmental Protection and Safety Engineering of University of South ChinaChina;School of Public Health, China
关键词:
Biosorption;Mechanism;Uranium
摘要:
Research on the ability and mechanism of genetically recombinant E. coli DH5α containing DSR A gene to enrich uranium under culture conditions provides a theoretical basis for the application of the bacteria in the treatment of uranium pollution. By exploring the influence of factors such as the initial concentration of uranium, culture time, and inoculation amount on the characteristics of uranium enrichment in genetically recombinant E. coli, using FTIR, SEM-EDS, XPS and XRD explore the mechanism of uranium-enriched bacteria. The results showed that when initial UO22+ concentration reach 600 mg/L, E. Coli D1 could not survived, indicated that the maximum tolerance concentration is lower than 600 mg/L. While concentration between 0∼500 mg/L, strains D1 can grow normally and has the ability to enrich uranium. In the prime stage, strains D1 resist toxics through release inorganic phosphates to precipitate UO22+ on cell wall, after 96 h, most UO22+ were transferred into cytoplasm and metabolized into U(IV) which is less toxic. In the metabolize process, all groups involved in metabolizing UO22+, especially protein contain groups like hydroxyl, amine and carboxyl paly a huge role. It shows that within a certain concentration rage, strains D1 has a good enrichment effect on uranium under culture conditions. © 2021 Elsevier Inc.
语种:
英文
展开