Silver Nanowire Synthesis and Applications in Composites: Progress and Prospects
作者:
Fu, Danning;Yang, Rendang;Wang, Yang;Wang, Ruibin;Hua, Feiguo
期刊:
Advanced Materials Technologies ,2022年7(11) ISSN:2365-709X
通讯作者:
Wang, Y;Hua, FG
作者机构:
[Yang, Rendang; Wang, Yang; Fu, Danning; Wang, Y] South China Univ Technol, State Key Lab Pulp & Paper Engn, Guangzhou 510640, Peoples R China.;[Wang, Ruibin] Univ South China, Coll Chem & Chem Engn, Hengyang 421001, Peoples R China.;[Hua, Feiguo; Hua, FG] Zhejiang Jinjiahao Green Nanomat Co Ltd, 37-1 Jinxing Ave, Quzhou 324404, Peoples R China.
通讯机构:
[Hua, FG ] Z;[Wang, Y ] S;South China Univ Technol, State Key Lab Pulp & Paper Engn, Guangzhou 510640, Peoples R China.;Zhejiang Jinjiahao Green Nanomat Co Ltd, 37-1 Jinxing Ave, Quzhou 324404, Peoples R China.
关键词:
application fields;preparation methods;silver nanowires;silver nanowire composites
摘要:
Silver nanowires (AgNWs) have gained increased interest as highly conductive and transparent nanomaterials with numerous applications across various fields. Owing to their unique properties (e.g., optical transparency, electrical conductivity, mechanical characteristics, and ease of processing), AgNWs have been extensively investigated for application in light-emitting diodes, solar cells, electrocatalysis, liquid crystal displays, wearable electronic devices, flexible nanosensors, and supercapacitors. In this review, recent advances in the synthesis of AgNWs (including the polyol, template, wet chemical, and photoreduction methods) are discussed, with a focus on their advantages and disadvantages in terms of AgNW structural regulation. Furthermore, the advantages and applications of AgNW composites, are comprehensively reviewed and analyzed, with a focus on energy storage and optoelectronics, sensors, electromagnetic interference shielding and absorbing materials, nanogenerators, and other applications. The prospects and challenges of AgNW composites in emerging applications are also proposed. © 2022 Wiley-VCH GmbH.
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英文
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Charged Nanochannels in Covalent Organic Framework Membranes Enabling Efficient Ion Exclusion
作者:
You, Xinda;Cao, Li;Liu, Yawei;Wu, Hong;Li, Runlai;...
期刊:
ACS Nano ,2022年16(8):11781-11791 ISSN:1936-0851
通讯作者:
Wu, Hong(wuhong@tju.edu.cn);Jiang, Zhongyi(zhyjiang@tju.edu.cn)
作者机构:
[Yang, Pengfei; Jiang, Zhongyi; Wu, Hong; Yuan, Jinqiu; Yang, Xiaoyu; You, Xinda; Ma, Yu; Zhang, Runnan; Cao, Li; Wang, Xiaoyao; Fan, Chunyang] Tianjin Univ, Sch Chem Engn & Technol, Key Lab Green Chem Technol, Minist Educ, Tianjin 300072, Peoples R China.;[Yang, Pengfei; Jiang, Zhongyi; Wu, Hong; Yuan, Jinqiu; Yang, Xiaoyu; You, Xinda; Ma, Yu; Zhang, Runnan; Cao, Li; Wang, Xiaoyao; Fan, Chunyang] Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Tianjin 300072, Peoples R China.;[Liu, Yawei] Chinese Acad Sci, Inst Proc Engn, Beijing Key Lab Ion Liquids Clean Proc, CAS Key Lab Green Proc & Engn,State Key Lab Multip, Beijing 100190, Peoples R China.;[Li, Runlai] Natl Univ Singapore, Dept Chem, Singapore 117549, Singapore.;[Xiao, Qianxiang] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.
通讯机构:
[Hong Wu; Zhongyi Jiang] K;Key Laboratory for Green Chemical Technology of Ministry of Education, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China<&wdkj&>Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin 300072, China<&wdkj&>Joint School of National University of Singapore and Tianjin University, International Campus of Tianjin University, Binhai New City, Fuzhou 350207, China<&wdkj&>Zhejiang Institute of Tianjin University, Ningbo, Zhejiang 315201, China<&wdkj&>Key Laboratory for Green Chemical Technology of Ministry of Education, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China<&wdkj&>Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin 300072, China<&wdkj&>Tianjin Key Laboratory of Membrane Science and Desalination Technology, Tianjin University, Tianjin 300072, China
关键词:
charged nanochannel;covalent organic framework membrane;nanoconfined electrostatic interaction;ion exclusion;nanofiltration
摘要:
Controllable ion transport through nanochannels is crucial for biological and artificial membrane systems. Covalent organic frameworks (COFs) with regular and tunable nanochannels are emerging as an ideal material platform to develop synthetic membranes for ion transport. However, ion exclusion by COF membranes remains challenging because most COF materials have large-sized nanochannels leading to nonselective transport of small ions. Here we develop ionic COF membranes (iCOFMs) to control ion transport through charged framework nanochannels, the interior surfaces of which are covered with arrayed sulfonate groups to render superior charge density. The overlap of an electrical double layer in charged nanochannels blocks the entry of co-ions, narrows their passageways, and concomitantly restrains the permeation of counterions via the charge balance. These highly charged large-sized nanochannels within the iCOFM enable ion exclusion while maintaining intrinsically high water permeability. Our results reveal possibilities for controllable ion transport based on COF membranes for water purification, ionic separation, sensing, and energy conversion. © 2022 American Chemical Society. All rights reserved.
语种:
英文
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Efficient reduction of uranyl under aerobic conditions by sodium and potassium co-doped carbon nitride
作者:
Li, Yuehuan;Shi, Lang;Mao, Yu;Zhang, Yu;Wang, Hongqing
期刊:
Chemical Engineering Journal ,2022年446:136872 ISSN:1385-8947
通讯作者:
Wang, Hongqing(hqwang@usc.edu.cn)
作者机构:
[Wang, Hongqing; Shi, Lang; Zhang, Yu; Li, Yuehuan] Univ South China, Coll Chem & Chem Engn, Hunan Key Lab Design & Applicat Actinide Complexes, Hengyang 421001, Hunan, Peoples R China.;[Mao, Yu] Hunan Univ, Coll Chem & Chem Engn, Joint Int Ctr CO2 Capture & Storage iCCS, Prov Hunan Key Lab Costeffect Utilizat Fossil Fuel, Changsha 410082, Peoples R China.
通讯机构:
[Wang, H.] H;Hunan Key Laboratory for the Design and Application of Actinide Complexes, Hunan, China
关键词:
U(VI);Photoreduction;Aerobic conditions;CD-NaK;Benzyl alcohol
摘要:
It is still a challenge for photocatalytic reduction of uranyl and maintaining catalyst stability under aerobic conditions. Herein, a catalyst of sodium–potassium co-doped g-C3N4 (CD-NaK) was obtained to remove Hexavalent Uranium (U(VI)) by photocatalytic reduction under aerobic conditions. And the CD-NaK was characterized by XRD, XPS and other methods. Furthermore, DFT calculations and XRD revealed that Na was doped in-plane while K was doped in-plane and interlayer, enhancing holes and electrons separation performance. Moreover, the removal rate of U(VI) could be achieved nearly 100% after 20 mins of visible irradiation in the presence of air over CD-NaK(30). The photocatalytic activity has the order: CD-NaK(30) > SD-Na > SD-K > CN. Additionally, when the atmosphere of the reaction system was air, the photocatalytic activity of CD-NaK(30) to uranyl was 4.6 times higher than that of pure nitrogen atmosphere in the present of benzyl alcohol, and CD-NaK(30) displayed good reusability and stability with the removal rate > 96% even after five cycles. Interestingly, the effect of the amount of oxygen on catalytic reduction and the role of oxygen were elucidated. Finally, a novel uranyl reduction mechanism has been supposed. © 2022 Elsevier B.V.
语种:
英文
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Waste non-burn-free brick derived sulfhydryl functioned magnetic zeolites and their efficient removal of uranium(VI) ions
作者:
Ai, Yong;Yin, Na;Ouyang, Yanquan;Xu, Yuanxin;Yang, Pengfei*
期刊:
Applied Surface Science ,2022年571:151241- ISSN:0169-4332
通讯作者:
Yang, Pengfei
作者机构:
[Xu, Yuanxin; Ouyang, Yanquan; Ai, Yong; Yang, Pengfei; Yin, Na] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.;[Xu, Yuanxin; Ouyang, Yanquan; Ai, Yong; Yang, Pengfei; Yin, Na] Univ South China, Hunan Key Lab Design & Applicat Actinide Complexe, Hengyang 421001, Peoples R China.
通讯机构:
[Yang, Pengfei] U;Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.
关键词:
Abandoned non-burning brick;Zeolite;Magnetization;Sulfhydrylization;Adsorption;Uranium (VI) ion
摘要:
Utilising the general waste such as non-burning brick as raw materials to prepare low-cost zeolite is in line with the green chemical industry and can achieve the purpose of treating waste with waste. Here we use the abandoned non-burning brick powder as raw material, the sulfhydryl functionalized magnetic zeolite composites (MZ-SH) were prepared by combining a series of methods such as hydrothermal synthesis, high temperature melting magnetization, and grafting technology. The samples were characterized by SEM, EDS, XRD, XPS, and FT-IR. The adsorption behavior of MZ-SH on uranyl ions was systematically studied. The results show that the equilibrium adsorption capacity of MZ-SH to uranium(VI) ions was 1285.86 mg/g under the optimal adsorption conditions with t of 270 mins, T at 35 ℃, C0 being 35 mg/L, pH at 6.0, and m by 0.025 g/L. Its adsorption isotherm complies with the Langmuir adsorption model, while the adsorption kinetics conforms to the quasi-second-order adsorption kinetic model. The adsorption type is mainly chemical adsorption with type of monolayer distribution on the surface. Adsorption thermodynamics shows that the adsorption process was spontaneous at 25–45 ℃. FT-IR and XPS analysis showed that sulfhydryl, –OH, Al-O and Si-O played an important role in the adsorption process of uranium (VI) ions by MZ-SH. It indicates that the uranium(VI) ions prefer binding with –OH and sulfhydryl groups and there is also showing ion exchange between uranium(VI) ions and Al-O and Si-O groups. © 2021
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英文
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Dipole-Dipole and Anion-π+ Interaction Manipulation Synergistically Enhance Intrinsic Antibacterial Activities of AIEgens
作者:
Jiang, Guoyu;Hu, Rong;Li, Chunbin;Gong, Jianye;Wang, Jianguo;...
期刊:
Chemistry - A European Journal ,2022年28(63) ISSN:0947-6539
通讯作者:
Wang, Jianguo(wangjg@iccas.ac.cn);Qin, Anjun(msqinaj@scut.edu.cn);Zhong Tang, Ben(tangbenz@cuhk.edu.cn)
作者机构:
[Gong, Jianye; Li, Chunbin; Jiang, Guoyu; Wang, Jianguo] Inner Mongolia Univ, Coll Chem & Chem Engn, Inner Mongolia Key Lab Fine Organ Synth, Hohhot 010021, Peoples R China.;[Qin, Anjun; Hu, Rong] South China Univ Technol, State Key Lab Luminescent Mat & Devices, Guangzhou 510640, Peoples R China.;[Lam, Jacky W. Y.] Hong Kong Univ Sci & Technol, Chinese Natl Engn Res Ctr Tissue Restorat & Recon, Hong Kong Branch, Kowloon, Clear Water Bay, Hong Kong, Peoples R China.;[Tang, Ben Zhong] Chinese Univ Hong Kong Shenzhen, Shenzhen Inst Aggregate Sci & Technol, Sch Sci & Engn, Shenzhen 518172, Guangdong, Peoples R China.;[Hu, Rong] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.
通讯机构:
[Wang, J.] C;[Qin, A.; Zhong Tang, B.] S;School of Science and Engineering, Guangdong, China;State Key Laboratory of Luminescent Materials and Devices, China;College of Chemistry and Chemical Engineering, China
关键词:
aggregation-induced emission;anion-π+ interaction;antibacterial activity;dipole-dipole interaction;pathogenic bacteria infections
摘要:
A synergistic manipulation strategy of dipole‐dipole and anion‐π+ interaction is proposed to enhance the binding affinity of dyes toward pathogenic bacteria and to construct highly efficient luminescence‐guided antimicrobials with aggregation‐induced emission (AIE) feature independent of light and the surrounding oxygen. Abstract Pathogenic bacteria infections, especially multidrug resistant bacteria infections have aroused worldwide attention due to their severe threats to human beings. Thus, the development of highly effective antibacterial reagents is very important. However, the design of antimicrobials is still quite challenging for the lack of a universal design strategy. Here, a synergistic manipulation strategy of dipole‐dipole and anion‐π+ interaction is proposed for constructing highly efficient antimicrobials with aggregation‐induced emission (AIE) feature. Firstly, four anion‐π+‐type AIE luminogens were designed and synthesized. Due to the electron‐donating and hydrophilic characteristic of methoxy groups, 3MOTPO containing three methoxy groups showed the largest dipole moment (5.06 Debye) and dual anion‐π+ interactions in the solid state. Driven by both dipole‐dipole and anion‐π+ interactions, 3MOTPO showed the strongest bacterial binding ability and the best antibacterial activities (MIC90=3.76 μM). The work offers a deep insight into the rational design of highly efficient antimicrobials for luminescence‐guided antibacterial study.
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英文
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Complexation and enantioselectivity of novel bridge-like uranyl-2-((1Z,9Z)-9-(2-Hydroxyphenyl)-3,5,6,8-tetrahydrobenzo[h][1,4,7,1 0] dioxadiazacyclododecin-2-yl)-5-methoxyphenol with chiral organophosphorus pesticide enantiomers of R/S-malathions
作者:
Tao, Xuebing;Yang, Rong;Xiao, Yang;Liao, Lifu;Xiao, Xilin;...
期刊:
Environmental Technology ,2022年43(22):3378-3389 ISSN:0959-3330
通讯作者:
Nie, Changming(Niecm196132@163.com)
作者机构:
[Yang, Rong; Tao, Xuebing; Xiao, Xilin; Liao, Lifu; Nie, Changming; Xiao, Yang] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.;[Yang, Rong; Tao, Xuebing; Nie, Changming; Xiao, Yang] Key Lab Hunan Prov Design & Applicat Nat Actinide, Hengyang 421001, Peoples R China.
通讯机构:
[Changming Nie] S;School of Chemistry and Chemical Engineering, University of South China, Hengyang, People’s Republic of China<&wdkj&>Key Laboratory of Hunan Province for Design and Application of Natural Actinide Complexes, Hengyang, People’s Republic of China
关键词:
Bridge-like uranyl-salophen;R/S-malathions;chiral organophosphorus pesticide;density functional theory;enantioselectivity
摘要:
Designing new uranyl complexes with enantioselectivity is of great significance for the identification and separation of enantiomers of chiral pesticides. In this paper, a new asymmetric rigid uranyl-2-((1Z,9Z)-9-(2-Hydroxyphenyl)-3,5,6,8-tetrahydrobenzo[h][1,4,7,10] dioxadiaza-cyclododecin-2-yl)-5-methoxyphenol(Uranyl-HTDM) was designed, we used Uranyl-HTDM as a receptor to selectively coordinate with the guests of the chiral organophosphorus pesticide R/S-malathions(R/S-MLTs) to explore the receptor's enatioselectivity recognition of the chiral guests of R/S-MLTs. Density functional theory (DFT) method was used to comprehensively study the complexation mode of the receptor with enantiomers. The results showed that the U of Uranyl-HTDM could coordinate with both the thiophosphoryl sulfur and carbonyl oxygens of R/S-MLTs in different environments, respectively. The thermodynamics calculations further indicated that the receptor could selectively recognize the thiophosphoryl sulfur and carbonyl oxygen atoms of R/S-malathions, and the complexation abilities of Uranyl-HTDM to the R/S-malathions under different solvents were not the same. The smaller the polarity of solvents, the stronger the complexation ability of Uranyl-HTDM with R-malathion, toluene was an ideal solvent with large G change and enatioselectivity coefficient of 99.55%. The study provides useful references for the design of new uranyl-salophens and for the experimental study on the molecular recognition of chiral organophosphorus pesticides. © 2021 Informa UK Limited, trading as Taylor & Francis Group.
语种:
英文
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Preface to special column on visible-light-driven catalytic organic synthesis
作者:
何卫民
期刊:
催化学报 ,2022年43(3):547 ISSN:0253-9837
作者机构:
[何卫民] School of Chemistry and Chemical Engineering, University of South China
摘要:
<正>Visible-light-driven organic reactions have emerged as important and promising strategies for the construction of various value-added compounds under mild conditions owing to the advantages of operation simplicity and high efficiency. The development of novel reaction procedures for the synthesis of significant molecules and useful building blocks for further applications is highly desirable.
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英文
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Theoretical insights into the separation of Am(iii)/Eu(iii): designing ligands based on a preorganization strategy
作者:
Lei, Xia-Ping;Wu, Qun-Yan;Wang, Cong-Zhi;Lan, Jian-Hui;Chai, Zhi-Fang;...
期刊:
Dalton Transactions ,2022年14(43):16659-16667 ISSN:1477-9226
通讯作者:
Wu, Qun-Yan(wuqy@ihep.ac.cn);Shi, Wei-Qun(shiwq@ihep.ac.cn)
作者机构:
[Lei, Xia-Ping; Wu, Qun-Yan; Chai, Zhi-Fang; Wang, Cong-Zhi; Lan, Jian-Hui; Shi, Wei-Qun] Chinese Acad Sci, Inst High Energy Phys, Lab Nucl Energy Chem, Beijing 100049, Peoples R China.;[Lei, Xia-Ping; Nie, Chang-Ming] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.
通讯机构:
[Lei, Xia-Ping] L;Laboratory of Nuclear Energy Chemistry, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, 100049, China.
摘要:
Separation of trivalent actinide (An(iii)) and lanthanide (Ln(iii)) is a worldwide challenge of nuclear waste treatment. Designing ligands with efficient An(iii)/Ln(iii) separation performance is still one of the key issues for the disposal of accumulated radioactive waste and the recovery of minor actinides. Recently, N-heterocyclic ligands modified with amide groups have shown excellent An(iii)/Ln(iii) separation performance. The preorganized structure of the ligands has a great impact on the An(iii)/Ln(iii) separation performance. We theoretically investigated the extraction behaviors of Am(iii) and Eu(iii) using phenanthroline (L1 and L2) and bipyridine (L3 and L4) based ligands with a completely or partially preorganized structure. The properties of these ligands and their coordination structures, bonding nature and thermodynamic behaviors with the Am(iii) and Eu(iii) complexes have been systematically studied in a theoretical fashion. The analyses of the bonding nature suggest that the Am-N bonds possess more covalence than the Eu-N bonds. The thermodynamic results indicate that L2 with a completely preorganized structure has the strongest extraction ability and the best Am(iii)/Eu(iii) selectivity, while L3 with the most flexible skeleton appears to have the weakest extraction ability and the lowest Am(iii)/Eu(iii) selectivity. And L1 and L4 have similar performances with regard to Am(iii)/Eu(iii) selectivity. The results suggest that a certain degree of preorganization of the ligand structure can enhance the extraction ability and Am(iii)/Eu(iii) selectivity. This work provides valuable information for designing efficient ligands for An(iii)/Ln(iii) separation by the preorganization strategy. © 2022 The Royal Society of Chemistry.
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英文
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A Cascade Nanozyme with Amplified Sonodynamic Therapeutic Effects through Comodulation of Hypoxia and Immunosuppression against Cancer
作者:
Tao, Na;Li, Huihuang;Deng, Liu* ;Zhao, Senfeng;Ouyang, Jiang;...
期刊:
ACS Nano ,2022年16(1):485-501 ISSN:1936-0851
通讯作者:
Deng, Liu;Liu, YN
作者机构:
[Deng, Liu; Wen, Mei; Zhao, Senfeng; Liu, You-Nian; Zeng, Ke; Chen, Wansong; Tao, Na; Ouyang, Jiang] Cent South Univ, Coll Chem & Chem Engn, Hunan Prov Key Lab Micro & Nano Mat Interface Sci, Changsha 410083, Hunan, Peoples R China.;[Li, Huihuang] Cent South Univ, Xiangya Hosp, Dept Urol, Changsha 410083, Hunan, Peoples R China.;[Zeng, Ke; Wei, Chuanwan] Univ South China, Coll Chem & Chem Engn, Hengyang 421001, Hunan, Peoples R China.
通讯机构:
[Deng, L; Liu, YN ] C;Cent South Univ, Coll Chem & Chem Engn, Hunan Prov Key Lab Micro & Nano Mat Interface Sci, Changsha 410083, Hunan, Peoples R China.
关键词:
tumor microenvironment adjustment;hypoxia alleviation;sonodynamic therapy;nanozymes;ROS
摘要:
The tumor microenvironment (TME) featured by immunosuppression and hypoxia is pivotal to cancer deterioration and metastasis. Thus, regulating the TME to improve cancer cell ablation efficiency has received extensive interest in oncotherapy. However, to reverse the immunosuppression and alleviate hypoxia simultaneously in the TME are major challenges for effective cancer therapy. Herein, a multifunctional platform based on Au nanoparticles and a carbon dots modified hollow black TiO2 nanosphere (HABT-C) with intrinsic cascade enzyme mimetic activities is prepared for reversing immunosuppression and alleviating hypoxia in the TME. The HABT-C NPs possess triple-enzyme mimetic activity to act as self-cascade nanozymes, which produce sufficient oxygen to alleviate hypoxia and generate abundant ROS. The theoretical analysis demonstrates that black TiO2 facilitates absorption of H2O and O2, separation of electron-holes, and generation of ROS, consequently amplifying the sonodynamic therapy (SDT) efficiency. Specifically, HABT-C exhibits favorable inhibition of immunosuppressive mediator expression, along with infiltrating of immune effector cells into the TME and reversing the immunosuppression in the TME. As a result, HABT-C can effectively kill tumor cells via eliciting immune infiltration, alleviating hypoxia, and improving SDT efficiency. This cascade nanozyme-based platform (HABT-C@HA) will provide a strategy for highly efficient SDT against cancer by modulation of hypoxia and immunosuppression in the TME. © 2022 American Chemical Society. All rights reserved.
语种:
英文
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Theoretical unraveling the complexation and separation of uranyl–ligand complexes towards chiral R/S-profenofos
作者:
Liu, Linfeng;Lu, Yao;Liao, Lifu;Xiao, Xilin;Nie, Changming
期刊:
Applied Organometallic Chemistry ,2022年36(6) ISSN:0268-2605
通讯作者:
Nie, CM
作者机构:
[Liu, Linfeng; Lu, Yao; Xiao, Xilin; Liao, Lifu; Nie, Changming] Univ South China, Sch Chem & Chem Engn, Hengyang, Peoples R China.;[Liu, Linfeng; Lu, Yao; Nie, CM; Xiao, Xilin; Liao, Lifu; Nie, Changming] Key Lab Hunan Prov Design & Applicat Nat Actinide, Hengyang 421001, Peoples R China.
通讯机构:
[Nie, CM ] K;Key Lab Hunan Prov Design & Applicat Nat Actinide, Hengyang 421001, Peoples R China.
关键词:
chiral organophosphorus pesticide;density functional theory (DFT);R/S-profenofos;separation factor;uranyl–ligand complexes
摘要:
The identification and separation of chiral pesticides R/S-profenofos are of great significance due to different biological toxicity of chiral isomers. In the study, we designed two novel ligands: (2,2′:6′,2″-terpyridin)-6-yl(5-methoxy-1H-pyrazol-1-yl) methanethione (TMMT) and (2,2′:6′,2″-terpyridin)-6-yl(5-methoxy-1H-pyrazol-1-yl) methanone (TMMO), and taking them as ligands coordinated with uranyl, two novel complexes [Uranyl-TMMT]2+ and [Uranyl-TMMO]2+ as receptors were successfully constructed. The complexation and enantioselectivity of two receptors towards R/S-profenofos as guests were systematically unraveled based on the density functional theory (DFT) method. The results showed that the receptor [Uranyl-TMMT]2+ containing thioamide group has stronger electron donating ability than the receptor [Uranyl-TMMO]2+ containing amide group. All analyses including Mayer bond order (MBO), quantum theory of atoms in molecules (QTAIM), localized orbital locator (LOL) function, molecular orbital, and infrared spectrum illustrated that the U-X (X = S, O) bonds play a larger role than the U-N bonds in the selective complexation of receptors towards guests; the U-S bond in [Uranyl-TMMT]2+ is more covalent than the U-O bond in [Uranyl-TMMO]2+. The thermodynamic calculations showed that the separation factors of [Uranyl-TMMT]2+ towards R/S-PFFs were between 8356 and 1219 in different solvents, and the separation factors of [Uranyl-TMMO]2+ towards R/S-PFFs were at range of 4951–710. The separation factors exhibited that two receptors have stronger coordination and complexation ability to S-PFF than to R-PFF, while [Uranyl-TMMT]2+ exhibited significantly greater recognition ability and enantioselectivity for guests R/S-PFFs molecules than the receptor [Uranyl-TMMO]2+. © 2022 John Wiley & Sons, Ltd.
语种:
英文
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Design and structural regulation of AIE photosensitizers for imaging-guided photodynamic anti-tumor application
作者:
Jia, Shaochuan;Yuan, Huanxiang;Hu, Rong
期刊:
Biomaterials Science ,2022年10(16):4443-4457 ISSN:2047-4830
通讯作者:
Yuan, Huanxiang(yhx@iccas.ac.cn);Hu, Rong(hurong@usc.edu.cn)
作者机构:
[Yuan, Huanxiang; Jia, Shaochuan] Beijing Technol & Business Univ, Coll Chem & Mat Engn, Dept Chem, Beijing 100048, Peoples R China.;[Hu, Rong] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.
通讯机构:
[Huanxiang Yuan] D;[Rong Hu] S;School of Chemistry and Chemical Engineering, University of South China, Hengyang 421001, P. R. China<&wdkj&>Department of Chemistry, College of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing 100048, P. R. China
摘要:
In recent years, photodynamic therapy (PDT) has become one of the important therapeutic methods for treating cancer. Aggregation-induced emission (AIE) photosensitizers (PSs) overcome the aggregation-caused quenching (ACQ) effects of conventional PSs in aggregation or high concentration states, showing enhanced reactive oxygen species (ROS) generating capacity and improved therapeutic efficiency. Meanwhile, connecting different donor and acceptor groups gives the PSs a lower energy level and the absorption/emission of a long wavelength, which makes the PSs produce more ROS and penetrate deeper into the tissue for imaging. As a promising tool for achieving efficient PDT applications, numerous studies have demonstrated the advantages and potential medical applications of AIE PSs in the diagnosis and treatment of various diseases. Herein, we outline the research progress of AIE PSs with different representative structures in fluorescence imaging and photodynamic anti-tumor therapy, and expound the design strategy of the donor-acceptor (D-A) framework for constructing practical AIE PSs in the past three years. Furthermore, this review addresses the underlying challenges and opportunities of AIE PSs in PDT, aiming to grasp the striving directions of the next generation of AIE PSs. © 2022 The Royal Society of Chemistry.
语种:
英文
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Tunable Nonlinearity in 2D Graphdiyne Oxide for High-Performance All-Optical Modulation
作者:
Wu, Leiming;Wei, Songrui;Zhang, Yule;Zhang, Ye;Xiang, Yuanjiang;...
期刊:
Advanced Optical Materials ,2022年10(12) ISSN:2195-1071
通讯作者:
Qin, YW;Zhang, H;Zhang, Y;Xiang, YJ
作者机构:
[Qin, Yuwen; Qin, YW; Wu, Leiming] Guangdong Univ Technol, Sch Informat Engn, Inst Adv Photon Technol, Guangzhou 510006, Peoples R China.;[Qin, Yuwen; Qin, YW; Wu, Leiming] Guangdong Univ Technol, Guangdong Prov Key Lab Informat Photon Technol, Guangzhou 510006, Peoples R China.;[Zhang, H; Zhang, Yule; Zhang, Han; Wei, Songrui] Shenzhen Univ, Collaborat Innovat Ctr Optoelect Sci & Technol, Shenzhen 518060, Peoples R China.;[Wei, Songrui] Shenzhen Univ, Coll Phys & Optoelect Engn, Interdisciplinary Ctr High Magnet Field Phys, Shenzhen 518060, Peoples R China.;[Zhang, Ye; Zhang, Y] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.
通讯机构:
[Zhang, H ] S;[Qin, YW ] G;[Xiang, YJ ] H;[Zhang, Y ] U;Guangdong Univ Technol, Sch Informat Engn, Inst Adv Photon Technol, Guangzhou 510006, Peoples R China.
关键词:
all-optical modulation;graphdiyne oxide;modulation depth;tunable nonlinearity
摘要:
2D atomically thin graphdiyne oxide (GDYO) nanosheets (NSs) are synthesized, and their nonlinear modulation is investigated. Generally, improving the modulation depth (MD) of all-optical modulation (AOM) requires a pump light with strong power, which limits the development of AOM technology in the design of low-power loss devices. In this study, an AOM system based on spatial self-phase modulation and spatial cross-phase modulation methods is proposed using 2D GDYO NSs. The results reveal that 2D GDYO exhibits tunable nonlinearity and high stability, which is desirable for designing the AOM system. Because of the excellent optical properties of 2D GDYO, a large MD of >98% is achieved for the proposed AOM with a low power of pump light, which is higher than most AOMs currently reported. Thus, GDYO is an excellent modulation material in AOM, which improves the application prospects of carbon nanomaterials in all-optical devices. © 2022 Wiley-VCH GmbH.
语种:
英文
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环氧大豆油化学接枝聚乳酸的制备及其性能
作者:
蔡垚;吴红枚;刘武;李端;范诗易;...
期刊:
材料研究学报 ,2022年36(1):73-80 ISSN:1005-3093
通讯作者:
Wu, Hongmei(wuhongmei2016@163.com)
作者机构:
[蔡垚; 吴红枚; 李端; 范诗易; 王洋洋] College of Chemistry and Chemical Engineering, University of South China, Hengyang;421000, China;[刘武] Dongguan Huilin New Material Technology Co. Ltd., Dongguan;523000, China;[蔡垚; 吴红枚; 李端; 范诗易; 王洋洋] 421000, China
通讯机构:
[Wu, H.] C;College of Chemistry and Chemical Engineering, University of South China, Hengyang, China
关键词:
复合材料;化学接枝;改性;环氧大豆油
摘要:
用化学改性方式将环氧大豆油(ESO)与用马来酸酐(MAH)改性过的PLA接枝(MPLA),制备了反应性增容剂ECP并提出其可能的接枝机理。用FT-IR、DSC、SEM等手段表征ECP,研究了制备ECP时4种加料方式和ESO与MAH基团的摩尔比对其接枝率和酸值的影响。结果表明:在MPLA阶段先加入1/3配方比的ESO,在化学接枝阶段加入剩余的ESO和全部的三乙胺,制备出的ECP接枝率最高达4.1514%;ESO与MAH基团的摩尔比为1时产物的接枝效果最好。ECP改性的PLA材料其综合性能优于ESO改性的PLA材料,ECP的加入使PLA的疏水性能提高。
语种:
中文
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Influence of twisted or planar linkers on the performance of quasi-two-dimensional fused perylene diimide acceptors for organic solar cells
作者:
Yin, Yuli;Liu, Ming;Guo, Fengyun;Gao, Shiyong;Zhang, Yong
期刊:
Dyes and Pigments ,2022年207:110787 ISSN:0143-7208
通讯作者:
Zhang, Yong(yongzhang@hit.edu.cn)
作者机构:
[Yin, Yuli] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.;[Gao, Shiyong; Guo, Fengyun; Liu, Ming; Yin, Yuli; Zhang, Yong] Harbin Inst Technol, Sch Mat Sci & Engn, Harbin 150001, Peoples R China.;[Zhang, Yong] Zhengzhou Univ, Sch Mat Sci & Engn, Zhengzhou 450001, Peoples R China.
通讯机构:
[Yong Zhang] S;School of Materials Science and Engineering, Harbin Institute of Technology, Harbin, 150001, PR China<&wdkj&>School of Materials Science and Engineering, Zhengzhou University, Zhengzhou, 450001, PR China
关键词:
Fused perylene diimide dimer;Structure -property relationship;Quasi -two-dimensional acceptor;Organic solar cells
摘要:
Quasi-two-dimensional (quasi-2D) fused perylene diimide building block is effective for constructing high-performance non-fullerene acceptors, while the exploration of their structure-property relationship remains critical, yet challenging. Herein, two quasi-2D non-fullerene acceptors (FPDI-V and FPDI-E) featuring vinylene or ethynylene linker were developed to reveal the effects of molecular geometry on photophysics, morphology and device performances. We observed that such minor chemical variations can lead to distinct difference on absorption spectra, energy levels, and the photovoltaic properties, but only have slight effects on crystallinity, molecular packing and film morphology. The resulting device based on PTB7-Th:FPDI-V delivered a power conversion efficiency of 7.53%, which is higher than those of FPDI-E based device (6.37%). The improved photovoltaic performance of FPDI-V with a twisted vinylene linker should come from the enhanced absorption coefficient, upshifted molecular energy levels, higher exciton dissociation rate, and weaker charge recombination. This result provides an updated idea for further designing and structural optimizing of quasi-2D non-fullerene acceptors. © 2022 Elsevier Ltd
语种:
英文
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N-Annulated Perylene Bisimide-Based Double-Cable Polymers with Open-Circuit Voltage Approaching 1.20 v in Single-Component Organic Solar Cells
作者:
Wang, Ruoyao;Xia, Dongdong;Jiang, Xudong;Zhao, Chaowei;Zhou, Shengxi;...
期刊:
ACS Applied Materials & Interfaces ,2022年14(42):47952-47960 ISSN:1944-8244
通讯作者:
Xia, Dongdong(xiadongdong@iccas.ac.cn);Xiao, Chengyi(xiaocy@mail.buct.edu.cn);Li, Weiwei(liweiwei@iccas.ac.cn)
作者机构:
[Li, Weiwei; Xia, Dongdong; Fang, Haisheng; Wang, Ruoyao; Zhou, Shengxi; Xiao, Chengyi] Beijing Univ Chem Technol, Beijing Adv Innovat Ctr Soft Matter Sci & Engn, Beijing 100029, Peoples R China.;[Li, Weiwei; Xia, Dongdong; Fang, Haisheng; Wang, Ruoyao; Zhou, Shengxi; Xiao, Chengyi] Beijing Univ Chem Technol, State Key Lab Organ Inorgan Composites, Nanchang 100029, Peoples R China.;[Jiang, Xudong] Univ South China, Coll Chem & Chem Engn, Hengyang 421001, Peoples R China.;[Zhao, Chaowei] Jiangxi Acad Sci, Inst Applied Chem, Nanchang, Peoples R China.;[Tang, Zheng; Wang, Jing] Donghua Univ, Coll Mat Sci & Engn, Ctr Adv Low Dimens Mat, State Key Lab Modificat Chem Fibers & Polymer Mat, Shanghai 201620, Peoples R China.
通讯机构:
[Dongdong Xia; Chengyi Xiao; Weiwei Li] B;Beijing Advanced Innovation Center for Soft Matter Science and Engineering & State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology, Beijing 100029, P. R. China<&wdkj&>Beijing Advanced Innovation Center for Soft Matter Science and Engineering & State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology, Beijing 100029, P. R. China<&wdkj&>Institute of Applied Chemistry, Jiangxi Academy of Sciences, Nanchang 330096, P. R. China
关键词:
N-annulated perylene bisimides;double-cable polymers;molecular symmetry;phase separation;single-component organic solar cells
摘要:
In this work, we have introduced single/double-sided N-annulated perylene bisimide (PBI) with deep energy levels into double-cable polymers with poly[1-(5-(4,8-bis(4-chloro-5-(2-ethylhexyl)thiophen-2-yl)-6-methylbenzo[1,2-b:4,5-b′]dithiophen-2-yl)thiophen-2-yl)-5,7-bis(2-ethylhexyl)-3-(5-methylthiophen-2-yl)-4H,8H-benzo[1,2-c:4,5-c′]dithiophene-4,8-dione] (PBDB-T-Cl) as a donor backbone, marking as s-PPNR and as-PPNR, according to the molecular symmetry. Both double-cable polymers displayed a high open-circuit voltage approaching 1.20 V in light of high energy level discrepancy between electron-donating and electron-withdrawing parts, which is the highest open-circuit voltage among double-cable-based single-component organic solar cell (SCOSC) devices. Additionally, the asymmetric polymer displayed improved absorption spectra, thereby promoting crystallization and phase separation. Consequently, the as-PPNR-based SCOSCs achieved a power conversion efficiency of 5.05% along with a higher short-circuit current density and fill factor than their s-PPNR-based counterparts. In this work, we have successfully incorporated N-annulated PBI into double-cable polymers and revealed the important effects on structural symmetry and phase separation of double-cable polymers for higher SCOSC performance. © 2022 American Chemical Society. All rights reserved.
语种:
英文
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Visible-Light Photosynthesis of CHF2/CClF2/CBrF2-Substituted Ring-fused Quinazolinones in Dimethyl Carbonate
作者:
Gui, Qing-Wen;Teng, Fan;Yang, Hao;Xun, Changping;Huang, Wen-Jie;...
期刊:
Chemistry - An Asian Journal ,2022年17(1):e202101139 ISSN:1861-4728
通讯作者:
He, Wei-Min(weiminhe2016@yeah.net)
作者机构:
[Gui, Qing-Wen; Teng, Fan; Yang, Hao; Xun, Changping; Huang, Wen-Jie; Lu, Zi-Qin; Zhu, Meng-Xue] College of Chemistry and Materials Science, Hunan Agricultural University, Changsha;410128, China;[Ouyang, Wen-Tao; He, Wei-Min] School of Chemistry and Chemical Engineering, University of South China, Hengyang;421001, China;[Gui, Qing-Wen; Teng, Fan; Yang, Hao; Xun, Changping; Huang, Wen-Jie; Lu, Zi-Qin; Zhu, Meng-Xue] 410128, China
通讯机构:
[He, W.-M.] S;School of Chemistry and Chemical Engineering, China
关键词:
cascade radical reactions;difluoromethylation;dimethyl carbonate;metal-free;ring-fused quinazolinones
摘要:
With eco-friendly and sustainable CO2-derived dimethyl carbonate as the sole solvent, the visible-light-induced cascade radical reactions have been established as a green and efficient tool for constructing various CHF2/CClF2/CBrF2-substituted ring-fused quinazolinones. © 2021 Wiley-VCH GmbH
语种:
英文
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In-depth study of the heme-binding ability to five heavy metals: Hg, Cd, Pb, Cr, and As
作者:
Lan, Wenbo;Wang, Xiaofeng;Kong, Xianghe;Nie, Changming
期刊:
Applied Organometallic Chemistry ,2022年36(10) ISSN:0268-2605
通讯作者:
Wang, Xiaofeng(wangxf20161123@126.com)
作者机构:
[Lan, Wenbo; Wang, Xiaofeng] Xiannan Univ, Sch Publ Hlth, Chenzhou 423000, Hunan, Peoples R China.;[Kong, Xianghe; Nie, Changming] Univ South China, Sch Chem & Chem Engn, Hengyang 421000, Hunan, Peoples R China.
通讯机构:
[Xiaofeng Wang] S;School of Public Health, Xiannan University, Chenzhou, Hunan, China
关键词:
binding energy;density functional theory;frontier molecular orbital energy level;heme;Wiberg bond indices
摘要:
The molecular structural characteristics of the complexes formed by the substitution of the central atom of heme (iron, Fe) by mercury (Hg), cadmium (Cd), lead (Pb), chromium (Cr), or arsenic (As) were studied using density functional theory (DFT). The simulated infrared and ultraviolet–visible spectra, Wiberg bond levels, frontier molecular orbital energy levels, and the binding capacity of the heme ligand to the central atom were assessed for all complexes. The results showed that when Fe was replaced by Hg, Cd, Pb, Cr, or As, the resulting complex was stable, with unique spectroscopic characteristics. Interestingly, the binding capacity of the heme ligand to Pb was about 10 times greater than that of the heme ligand to Fe and more than 10 times greater than that of the heme ligand to any of the other four heavy metals. The complex in which Fe was replaced by Cd had the greatest chemical stability. These results will provide an important reference for the future pollution control programs and will support efforts to enrich the five studied heavy metals using heme ligands, especially the specific capture of Pb and the enrichment of Cd. © 2022 John Wiley & Sons Ltd.
语种:
英文
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Referential modification strategy based on phenolic hydroxyl-containing KSA luminogens for ER-targeting probe construction
作者:
Deng, Qiyun;Ding, Keke;Li, Yin;Jiao, Yawen;Hu, Rong;...
期刊:
Biomaterials ,2022年289:121767 ISSN:0142-9612
通讯作者:
Wang, Zhiming(wangzhiming@scut.edu.cn);Hu, Rong(hurong@usc.edu.cn);Zhang, Tian(tzhang@sdut.edu.cn)
作者机构:
[Deng, Qiyun; Hu, Rong; Wang, Zhiming; Li, Yin; Tang, Ben Zhong] South China Univ Technol, AIE Inst, Ctr Aggregat Induced Emiss, State Key Lab Luminescent Mat & Devices,Guangdong, Guangzhou 510640, Peoples R China.;[Hu, Rong] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.;[Jiao, Yawen; Zhang, Tian] Shandong Univ Technol, Sch Chem & Chem Engn, Zibo 255049, Peoples R China.;[Tang, Ben Zhong] Chinese Univ Hong Kong, Shenzhen Inst Aggregate Sci & Technol, Sch Sci & Engn, Shenzhen 518172, Guangdong, Peoples R China.;[Ding, Keke] First Affiliated Hosp Wannan Med Coll, Yijishan Hosp Wannan Med Coll, Dept Urol, 2 Zheshan Rd, Wuhu 241001, Peoples R China.
通讯机构:
[Rong Hu; Zhiming Wang] C;[Tian Zhang] S;Center for Aggregation-Induced Emission, AIE Institute, State Key Laboratory of Luminescent Materials and Devices, Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates, Center for Aggregation-Induced Emission, South China University of Technology, Guangzhou, 510640, PR China<&wdkj&>School of Chemistry and Chemical Engineering, University of South China, Hengyang, 421001, PR China<&wdkj&>School of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo, 255049, PR China<&wdkj&>Center for Aggregation-Induced Emission, AIE Institute, State Key Laboratory of Luminescent Materials and Devices, Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates, Center for Aggregation-Induced Emission, South China University of Technology, Guangzhou, 510640, PR China
关键词:
Aggregation-induced emission;Endoplasmic reticulum targeting;Keto-salicylaldehyde azine;Phenolic hydroxyl;Photo-dynamic therapy
摘要:
The endoplasmic reticulum (ER) plays essential roles in various physiological processes and is intimately connected to kinds of diseases. The development of ER-targeting theranostic agents is highly demanded for precise treatments, however, the effective and referential strategies for the construction of ER-targeting probes are limited. Herein, we developed series of ER-targeting luminogens based on keto-salicylaldehyde azine (KSA) framework by introducing phenolic hydroxyl group, which present good theranostic performance with selective enrichment in ER. Under systematical structure modulation, the key role of phenolic hydroxyl group at K-terminal in ER-targeting was experimentally confirmed. Besides, the cyanobenzyl moiety at S-terminal can enhance the luminous efficiency and improve cellular uptake ability. Moreover, the generated reactive oxygen species (ROS) of these KSA derivatives can efficiently trigger ER stress to induce the apoptosis of cancer cells, resulting in the effective inhibition of tumor cells both in vitro and in vivo. Therefore, this feasible modification strategy of inserting phenolic hydroxyl group to common multi-aryl-based luminogens provides a reliable and referential approach for ER-targeting probe establishment.
语种:
英文
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A comparative study of the effect of multidimensional carbon fillers on polystyrene using supercritical carbon dioxide foaming
作者:
Jian, Lingfeng;Fan, Tianju;Weng, Mengman;Yu, Wentao;Chen, Weipeng;...
期刊:
Diamond and Related Materials ,2022年130:109495 ISSN:0925-9635
通讯作者:
Min, Yonggang(ygmin@gdut.edu.cn);Wang, Ruibin(rbwang@usc.edu.cn)
作者机构:
[Yu, Wentao; Weng, Mengman; Luo, Jiangrong; Liang, Junkai; Fan, Tianju; Chen, Weipeng; Jian, Lingfeng; Min, Yonggang] Guangdong Univ Technol, Ctr Emerging Mat & Technol, Sch Mat & Energy, Guangzhou 510006, Guangdong, Peoples R China.;[Wang, Ruibin] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.
通讯机构:
[Yonggang Min; Ruibin Wang] S;School of Materials and Energy, Center of Emerging Material and Technology, Guangdong University of Technology, Guangzhou, Guangdong 510006, China<&wdkj&>School of Chemistry and Chemical Engineering, University of South China, Hengyang 421001, China
关键词:
Supercritical CO2;Multidimensional carbon materials;Thermal insulation;Polystyrene foam
摘要:
Due to its low thermal conductivity on average (~0.039 W/(m·K)), supercritical expanded polystyrene (PS) foam could be used as an insulation material in buildings to save energy and minimize the maintenance costs. However, the specific solubilizing and fast diffusing behavior of CO2 in PS limited the formation of micropores and the further increase of macropores, which resulted in on limited decrease in thermal conductivity. In this study, one-dimensional carbon nanotubes, two-dimensional graphene, and three-dimensional activated carbon were loaded on PS using supercritical CO2 foaming. The results demonstrated that all these three carbon nanomaterials doped on PS could generate more micropores and macropores during foaming. Moreover, the composite PS foams presented much lower specific thermal conductivity (0.360 cm3·W/(g·m·K)), higher cell density (up to 3.23 × 1014 cell/cm3), and compressive modulus (up to 1.66 MPa), overwhelming those of pure PS. Particularly, the continuous infrared thermography measurements found that two-dimensional graphene thermally outperformed the others, meaning comparatively better heat insulation effect after foaming. Therefore, multidimensional carbon nanomaterials were promising to minimize the negative environmental impact of PS foaming while comprehensively reinforcing it. © 2022
语种:
英文
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Biocomputation with MnTiO3 Piezoelectric Enzymes for Programed Catalysis of Tumor Death
作者:
Xu, Qianqian;Gao, Xinyu;Wen, Mei;Liu, Yihong;Li, Yuqing;...
期刊:
ACS Applied Materials & Interfaces ,2022年14(24):28199-28210 ISSN:1944-8244
通讯作者:
Wen, Mei(mei_wen@csu.edu.cn);Chen, Wansong(chenws@csu.edu.cn)
作者机构:
[Xu, Qianqian; Gao, Xinyu; Wen, Mei; Liu, Yihong; Li, Yuqing; Wu, Xianbo; Zou, Yuyan; Li, Jianghua; Liu, You-Nian; Chen, Wansong] Hunan Provincial Key Laboratory Of Micro & Nano Materials Interface Science, College Of Chemistry And Chemical Engineering, Central South University, Hunan, Changsha;410083, China;[Wei, Chuanwan] School Of Chemistry And Chemical Engineering, University Of South China, Hunan, Hengyang;421001, China;[Li, Xilong] Hefei National Laboratory For Physical Science At Microscale, University Of Science And Technology Of China, Hefei
通讯机构:
[Wen, M.; Chen, W.] H;Hunan Provincial Key Laboratory Of Micro & Nano Materials Interface Science, College Of Chemistry And Chemical Engineering, Central South University, Hunan, Changsha, China
关键词:
artificial enzyme;cancer;nanomedicine;oxidative stress;piezoelectricity
摘要:
Catalytic nanomedicine, especially artificial enzymes, exhibit obvious merits over traditional nanomedicine. However, the lack of controllability over an enzymatic process seriously challenges the therapeutic performance. Herein, we present a concept of using piezoelectric enzymes in combination with biocomputation ability. As a paradigm, MnTiO3 nanodisks were prepared with multiple enzyme-mimicking activity, including glutathione oxidase, peroxidase, and catalase. Different from the conventional artificial enzymes, the enzymatic activity of MnTiO3 nanodisks was activated by ultrasound and switched by a tumor microenvironment, which allows precise control over enzymatic catalysis in tumors. By virtue of the multiple artificial enzyme activity of MnTiO3 nanodisks, a biocomputing platform was constructed based on a Boolean logic-based algorithm. With ultrasound and tumor microenvironment as input signals, cytotoxicity was output via logic-based biocomputation for programed tumor killing. The concept of piezoelectric enzymes together with a biocomputation strategy provides an intelligent and effective approach for catalytic tumor eradication. © 2022 The Authors. Published by American Chemical Society.
语种:
英文
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