作者:
Yang Fan;SuFang Chen;Zhang Qin;CuiMing Zhu;Chen Jie;...
期刊:
World Health Digest,2012年(51):6-8
作者机构:
Department ofMicrobiology and Immunology,Xiang Nan college of Medicine Department of basic medicine,423000;Institute of Pathogenic Biology,Nanhua University,Hengyang,Hunan,421001
关键词:
human papillomavirus type 18(HPV18);E2;IL-12;vaccine;human papillomavirus type 18(HPV18);E2;IL-12;vaccine
摘要:
Objective:To study the effectiveness of human papillomavirus type 18 E2 gene (HPV18-E2) vaccine and interleukin-12(IL-12) on their immune effects. Methods:Thirty-five Balb/c female mice aged 6-8-week-old were randomly divided into five groups (each n =7).The mice were given instramuscular injection of DNA vaccines at 2-week four 4 times(100mg/time).The tails were cut to draw blood at the 0,2,4,6 weeks,and then the mice were executed by eyeball blood letting at 8 weeks.ELISA was used for the quantitative detection of the specific lgG antibody in the srea of Balb/c mice and the cytokine IFN-γ and IL-4 in mice MTT assay.Results: after 8 weeks immunization, antibody IgA in E2 vaccine group andE2 +IL-12 vaccine group was statistically increased as compared with that of control group, and the difference was statistically significant (P<0.01). IFN-γand IL-4 levels of mice spleen lymphocyte culture supernatant inE2 group and E2 + IL-12 were significantly higher than other control groups (P<0.01). the spleen lymphopoiesis activeness of E2 + IL-12 group was significant enhanced as compared with the E2 group, there were statistically significant differences (P<0.01) . Conclusions: E2 DNA vaccine combined with IL-12 immune mice can effectively induce cell-mediated immunity and humoral immune responses, their capabilities of inducing immune response might be more stronger than that of single one.
作者机构:
School of Architecture, State Key Laboratory of Subtropical Building Science,South China University;Architecture Design and Research Institute, State Key Laboratory of Subtropical Building Science Sou
会议名称:
2012 International Conference on Electric Technology and Civil Engineering(2012 电子技术与土木工程国际会议 ICETCE 2012)
会议时间:
2012-05-18
会议地点:
三峡
会议论文集名称:
2012 International Conference on Electric Technology and Civil Engineering(2012 电子技术与土木工程国际会议 ICETCE 2012)论文集
摘要:
Urban design programming is a method to enhance the effectiveness and feasibility of development control tool in the market system. This article analysis the basic concept of urban design programming thought the reference of architecture and other relative programming theory. And then based on the business district of Guangzhou Huangpu Harbor urban design projects, it study for the main content and steps of programming methods, including: development environmental analysis, project positioning, operation strategy study and feasibility evaluation.
作者机构:
[余润兰; 邱冠周] School of Minerals Processing and Bioengineering, Central South University, Changsha 410083, Hunan, China;[杨懿全; 杨敬; 陈勇博; 胡鄂明; 张洪灿] School of Nuclear Resource and Nuclear Fuel Engineering, University of South China, Hengyang 421001, Hunan, China;[王清良] School of Minerals Processing and Bioengineering, Central South University, Changsha 410083, Hunan, China<&wdkj&>School of Nuclear Resource and Nuclear Fuel Engineering, University of South China, Hengyang 421001, Hunan, China
通讯机构:
School of Minerals Processing and Bioengineering, Central South University, China
作者机构:
[王永东; 李广悦; 丁德馨; 胡南; 邓钦文; 周支香] Key Discipline Lab. for National Defense for Biotechnology in Uranium Mining and Hydrometallurgy, University of South China, Hengyang 421001, Hunan, China
通讯机构:
Key Discipline Lab. for National Defense for Biotechnology in Uranium Mining and Hydrometallurgy, University of South China, China
作者机构:
College of Physics and Information Science, Hunan Normal University Changsha 410081/College of Mathematics and Physics, University of South China Hengyang 421001;College of Physics and Information Science,Hunan Normal University Changsha,410081
关键词:
直接控制;声场分布;合成模式;相控阵;声压;基础;加权;重量计算
摘要:
To optimize the acoustic field produced by phased array effectively and quickly, the pseudo-inverse method proposed previously is simplified. An approximate weight formula of sound pressure using a method of compensation to the amplitude and phase of the controlled sound pressure was presented. A multiple-focus field patterns based on the pseudo-inverse matrix algorithm can be obtained by presetting the value of the controlled sound pressure. A phased array comprised of 16 x 16 square elements is used for numerical simulation. The results show that the acoustic energy can be effectively deposited at the desired points, and the acoustic field can be synthesized quickly using the direct weight formula of the sound pressure. This study may offer an effective way for controlling the distribution of acoustic field in ultrasound hyperthermia.