关键词：
stroke;internet plus continuing nursing program;medication compliance;neurological function
摘要：
Background and Purpose: Ischemic stroke is a severe disorder with high rates of death and recurrence that causes disability in patients and for which there is currently no effective treatment. Internet-based rehabilitation helps patients with disability recover at home with the help of their household or family members in a nonclinical setting. However, the effects of the internet+continuing nursing (ICN) program on the recovery of patients after ischemic stroke remains unknown. Methods: In the present study, patients were treated with an ICN-based rehabilitation training program; subsequently, the Self-efficacy Scale for Chronic Disease, Questionnaire of Exercise Adherence, Motor Assessment Scale, Activities of Daily Living, and Stroke-specific Quality of Life were performed to evaluate the effects of the ICN program on patient self-confidence to persist with rehabilitation, functional exercise compliance, motor function, ability to live independently and quality of life following ischemic stroke. Results: We observed that, after the ICN intervention for 6 weeks and 3 months, the scores of Self-efficacy Scale for Chronic Disease, Questionnaire of Exercise Adherence, Motor Assessment Scale, Activities of Daily Living, and Stroke-specific Quality of Life in the ICN-treated group were significantly higher compared with those in the control group. Conclusion: These results suggested that the ICN program may promote the recovery of patients after ischemic stroke.
作者机构：
[Wang, Zhangyi; Wang, Yue; Zhang, Siai; Li, Xuechun; Zhu, Yue; Wang, Zhao] Tianjin Univ Tradit Chinese Med, Grad Sch, Tianjin, Peoples R China.;[Zhao, Haomei] Hebei Univ Chinese Med, Grad Sch, Shijiazhuang, Hebei, Peoples R China.;[Xiao, Luwei] Univ South China, Sch Nursing, Hengyang, Hunan, Peoples R China.;[Bao, Haiqin] Tianjin First Cent Hosp, Transplant Intens Care Unit, Tianjin, Peoples R China.;[Zhang, Yajun] Tianjin Univ Tradit Chinese Med, Affiliated Hosp 2, Operating Room, Tianjin 301617, Peoples R China.
通讯机构：
[Yajun Zhang] O;[Xiaoli Pang] S;School of Nursing, Tianjin University of Traditional Chinese Medicine, Tianjin, China<&wdkj&>Operating Room, The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China
关键词：
China;Elderly inpatient;Spiritual care needs;Spirituality;Stroke
期刊：
Frontiers in Energy Research,2022年9:821242 ISSN：2296-598X
通讯作者：
Feng, Y.
作者机构：
[Hu, Qingqing] Hunan Inst Technol, Sch Int Studies, Hengyang, Peoples R China.;[Li, Xue] Guangzhou Univ, Sch Econ & Stat, Guangzhou, Peoples R China.;[Feng, Yanhong] Univ South China, Sch Econ Management & Law, Hengyang, Peoples R China.
通讯机构：
[Feng, Y.] S;School of Economics, China
关键词：
green credit;Green total factor productivity;heterogeneous effects;mediating effects;Green technology innovation
摘要：
Understanding the effects of green credit on green total factor productivity (GTFP) is conductive to promoting the sustainable economy development. This paper examines the total effects, influence mechanism, and heterogeneous impacts of green credit on GTFP based on GTFP data of 30 provinces in China from 2008 to 2017. The findings show that, firstly, on the whole, green credit significantly increases GTFP, which is tested by the panel regression model. Secondly, according to the result of the panel quantile model, the increasing effect of green credit on GTFP is strengthened by the improvement of GTFP. Thirdly, green credit has heterogeneous impact on GTFP, which is reflected in economic development with different level, especially for different degrees of environmental regulation. Fourthly, under the full samples, green credit impacts GTFP through green technology innovation, but it has no effect on energy consumption structure. Besides, the influence mechanism is heterogeneous in the variation of sample characteristics. Finally, some significant policy recommendations are provided for policymakers based on these conclusions.
期刊：
Journal of Healthcare Engineering,2022年2022 ISSN：2040-2295
作者机构：
[Xu, Huilan; Wang, Rong] Cent South Univ, Xiangya Sch Publ Hlth, Changsha 410001, Hunan, Peoples R China.;[Duan, Gongxiang; Su, Yinhua; Liao, Li; Wang, Rong; Liao, Daqi; Li, Jianzhi] Univ South China, Sch Nursing, Hengyang 421001, Hunan, Peoples R China.;[Wu, Yuanyuan] Wuxi Mental Hlth Ctr, Wuxi 214000, Peoples R China.
摘要：
Rehabilitation intervention which refers to the functional training by caregivers with the aid of specialized nursing techniques and the progressive promotion of patients' training initiative, with the purpose of improving mobility and quality of life, is of great significance. The purpose of the study was to investigate the effect of the rehabilitation intervention-centered targeted nursing model on the cardiac function recovery and negative emotions in patients with acute myocardial infarction (AMI). A total of 120 AMI patients admitted to our hospital between January 2019 and January 2020 were selected as the study subjects and randomly divided into group A (n = 60) and group B (n = 60), in which the group B patients received routine nursing combined with rehabilitation intervention, while based on the treatment in group B, the patients in group A underwent rehabilitation intervention-centered targeted nursing model. Then, the cardiac function indexes, negative emotion score, levels of risk factors for heart failure, complication rate (CR), and the quality of life (QOL) of the patients were compared between the two groups. The cardiac function indexes of the patients after nursing in group A were significantly better than those in group B (P < 0.001); the negative emotion scores of the patients after nursing in group A were significantly lower than those in group B (P < 0.001); the levels of risk factors for heart failure of the patients after nursing in group A were significantly lower than those in group B (P < 0.001); the CR of the patients in group A at 15 d and 30 d after admission was significantly lower than that in group B (P < 0.05); the QOL scores of the patients after nursing in group A were significantly higher than those in group B (P < 0.001). Rehabilitation intervention-centered targeted nursing model can optimize cardiac function, weaken the levels of risk factors for heart failure, reduce the incidence of complications, improve psychological conditions, and enhance the quality of life in AMI patients, which is worthy of application and promotion in clinical practice.
摘要：
BackgroundOutdoor traffic-related air pollution has negative effects on respiratory health. In this study, we aimed to explore the effect of outdoor traffic-related air pollution on chronic obstructive pulmonary disease (COPD) in Guangzhou. MethodsWe enrolled 1,460 residents aged 40 years or older between 21 January 2014 and 31 January 2018. We administered questionnaires and spirometry tests. The distance of participants' residences or locations of outdoor activities from busy roads (as indicators of outdoor traffic-related air pollution), indoor air pollution, and smoking history were queried in the questionnaires. ResultsOf the 1,460 residents with valid survey and test results, 292 were diagnosed with COPD, with a detection rate of 20%. Participants who lived and did their outdoor activities near busy roads had a higher detection rate of COPD. Among residents living at distances of <50 meters, 50-199 meters, and more than 200 meters from busy roads, the detection rates were 20.6, 21.2, and 14.8%, respectively; the rates for outdoor activities at these distances were 23.8, 24.5, and 13.7%, respectively (p < 0.05). After adjusting for sex, age, smoking status, family history, and smoking index, the distance of outdoor activities from busy roads was an independent risk factor for COPD. Participants whose outdoor activities were conducted <50 meters and 50-199 meters of main roads had odds ratios of 1.54 (95% confidence interval 1.01-2.36) and 1.84 (95% interval 1.23-2.76) for the risk of COPD in comparison with a distance of more than 200 meters from busy roads. ConclusionsResidents of Guangzhou whose outdoor activities were close to busy roads had a high risk of COPD. Traffic-related air pollution presents a risk to human health and a risk of COPD.
作者机构：
[Tang, Beisha; Meng, Qingtuan] Univ South China, Multi Om Res Ctr Brain Disorders, Hengyang Med Sch, Affiliated Hosp 1, Hengyang 421001, Hunan, Peoples R China.;[Zhang, Wendiao; Xu, Sheng; Chen, Chao; Wang, Xuan] Cent South Univ, Xiangya Hosp 2, Ctr Med Genet, Changsha 410008, Hunan, Peoples R China.;[Zhang, Wendiao; Xu, Sheng; Chen, Chao; Wang, Xuan] Cent South Univ, Xiangya Hosp 2, Hunan Key Lab Med Genet, Sch Life Sci, Changsha 410008, Hunan, Peoples R China.;[Zhang, Wendiao; Xu, Sheng; Chen, Chao; Wang, Xuan] Cent South Univ, Xiangya Hosp 2, Dept Psychiat, Changsha 410008, Hunan, Peoples R China.;[Jiao, Chuan; Liu, Chunyu] SUNY Upstate Med Univ, Dept Psychiat, Syracuse, NY 13210 USA.
通讯机构：
[Chen, Chao] C;[Tang, Beisha] T;The First Affiliated Hospital, Multi-Omics Research Center for Brain Disorders, Hengyang Medical School, University of South China, 421001, Hengyang, Hunan, China.;Center for Medical Genetics & Hunan Key Laboratory of Medical Genetics, School of Life Sciences, and Department of Psychiatry, The Second Xiangya Hospital, Central South University, 410008, Changsha, Hunan, China.;Hunan Key Laboratory of Animal Models for Human Diseases, Central South University, 410008, Changsha, Hunan, China.
摘要：
Valproic acid (VPA) exposure as an environmental factor that confers risk of autism spectrum disorder (ASD), its functional mechanisms in the human brain remain unclear since relevant studies are currently restricted to two-dimensional cell cultures and animal models. To identify mechanisms by which VPA contribute to ASD risk in human, here we used human forebrain organoids (hFOs), in vitro derived three-dimensional cell cultures that recapitulate key human brain developmental features. We identified that VPA exposure in hFOs affected the expression of genes enriched in neural development, synaptic transmission, oxytocin signaling, calcium, and potassium signaling pathways, which have been implicated in ASD. Genes (e.g., CAMK4, CLCN4, DPP10, GABRB3, KCNB1, PRKCB, SCN1A, and SLC24A2) that affected by VPA were significantly overlapped with those dysregulated in brains or organoids derived from ASD patients, and known ASD risk genes, as well as genes in ASD risk-associated gene coexpression modules. Single-cell RNA sequencing analysis showed that VPA exposure affected the expression of genes in choroid plexus, excitatory neuron, immature neuron, and medial ganglionic eminence cells annotated in hFOs. Microelectrode array further identified that VPA exposure in hFOs disrupted synaptic transmission. Taken together, this study connects VPA exposure to ASD pathogenesis using hFOs, which is valuable for illuminating the etiology of ASD and screening for potential therapeutic targets.
期刊：
Frontiers in Psychiatry,2022年13:830541 ISSN：1664-0640
作者机构：
[Fu, Lili] Univ South China, Hainan Gen Hosp, Hainan Affiliated Hosp, Hengyang Med Sch, Haikou, Peoples R China.;[Liu, Liting; Huang, Weiyuan; Chen, Feng; Chen, Huijuan; Fu, Qingqing] Hainan Med Univ, Hainan Gen Hosp, Dept Radiol, Hainan Affiliated Hosp, Haikou, Peoples R China.;[Liu, Tao] Hainan Med Univ, Hainan Gen Hosp, Dept Neurol, Hainan Affiliated Hosp, Haikou, Peoples R China.
关键词：
Betel quid;betel quid dependent;Drug dependence;Resting-state fMRI;Percent amplitude of fluctuation
摘要：
ObjectiveThis study aimed to investigate brain spontaneous neural activity changes in betel quid dependence (BQD) chewers using the percent amplitude of fluctuation (PerAF) method. MethodsThis study included 48 BQD chewers. The healthy control (HC) group comprised 35 volunteers who were matched with BQD chewers in age, gender, and educational status. All subjects underwent resting-state functional magnetic resonance imaging (rs-fMRI) and neuropsychological tests. The PerAF method was used to identify BQD-related regional brain activity changes. An independent samples t-test was used to evaluate the PerAF difference across two groups. The association between PerAF changes and clinical features such as BQD scores, duration of BQD, Hamilton Depression Rating Scale-24 item (HAMD-24), and Hamilton Anxiety Rating Scale-14 item (HAMA-14) was evaluated by using Spearman's correlation analysis. It assessed the ability of the PerAF method to distinguish between BQD chewers and HCs using a receiver operating characteristic (ROC) curve. ResultsCompared to the control group, BQD chewers showed decreased PerAF in right anterior cingulate cortex (ACC), right middle frontal gyrus (MFG), right insula, right precuneus, left putamen, left supramarginal gyrus (SMG), and left cerebellum and increased PerAF in right orbitofrontal and left superior temporal gyrus (STG) [P < 0.05, Gaussian random field (GRF) corrected]. PerAF values of the right MFG and right ACC had a significant negative relationship with the duration of BQD (P < 0.05). The average values of PerAF in the left putamen, left cerebellum, and left STG showed significant discriminatory power in distinguishing BQD chewers from HCs, with relatively prime area under the curve (AUC) values. ConclusionOur findings suggested that betel quid chewing is associated with spontaneous neural activity alterations in the impulsivity areas (MFG and ACC), cognitive (MFG, ACC, precuneus, and the cerebellum), and reward (orbitofrontal, putamen, and insula) systems, which may be correlated with neuropathological mechanisms of BQD. Also, PerAF may be useful as a potential sensitive biomarker for identifying spontaneous brain activity changes in BQD chewers.
作者机构：
[Wang, Zhangyi; Yang, Zhihua; Pang, Xiaoli; Zhu, Yue; Yang, Yang] Tianjin Univ Tradit Chinese Med, Grad Sch, Tianjin, Peoples R China.;[Liang, Facun; Liu, Mengru] Huzhou Univ, Sch Nursing, Huzhou, Zhejiang, Peoples R China.;[Zhao, Xiqun] Tianjin Univ Tradit Chinese Med, Coll Culture & Hlth Commun, Tianjin, Peoples R China.;[Xiao, Luwei] Univ South China, Sch Nursing, Hengyang, Hunan, Peoples R China.;[Zhang, Yajun] Tianjin Univ Tradit Chinese Med, Affiliated Hosp 2, Operating Room, Tianjin, Peoples R China.
通讯机构：
[Huiying Weng] I;Intensive Care Unit (ICU), The First Affiliated Hospital of Huzhou University, Huzhou, Zhejiang, China
关键词：
Hospitalized elders;Severe chronic heart failure;Spiritual care needs;Attributes;Kano model
摘要：
OBJECTIVES: To investigate the spiritual care needs and their attributes among Chinese elders hospitalized for severe chronic heart failure (CHF) based on the Kano model, in order to provide a reference for improving the quality and satisfaction of spiritual care. METHODS: An observational design was implemented, and the STROBE Checklist was used to ensure quality reporting of the study. The demographic characteristics questionnaire, the Nurse Spiritual Therapeutics Scale, and the Kano model-based Nurse Spiritual Therapeutics Attributes Scale were used. A convenience sample of 451 patients were selected from 2 hospitals. Descriptive statistics, and Kano model were used to analyze the data. RESULTS: The total score of spiritual care needs was 29.95±7.51. Among the 12 items, 3 items were attractive attributes, all of which were located in Reserving Zone IV; 5 items were one-dimensional attributes, of which 3 were located in Predominance Zone I and 2 were located in Improving Zone II; 2 items were must-be attributes, all of which were located in Improving Zone II; and 2 items were indifference attributes, all of which were located in Secondary Improving Zone III. SIGNIFICANCE OF RESULTS: The spiritual care needs among Chinese elders hospitalized for severe CHF were moderate. The must-be and one-dimensional attributes mainly focus on "creating a good atmosphere" and "sharing self-perception" dimensions, while attractive attributes mainly focus on "sharing self-perception" and "helping thinking" dimensions. It is suggested that hospital authority should develop and innovate attractive attributes on the basis of maintaining and perfecting must-be and one-dimensional attributes, and objectively analyze and optimize indifference attributes.
期刊：
International Journal of Environmental Research and Public Health,2022年19(11):6529- ISSN：1661-7827
通讯作者：
Jie Zhang
作者机构：
[Zhang, Xiaoling; Wang, Liangqin; Li, Jie; Song, Xin; Zeng, Taotao; Yang, Jinhui; Chen, Shengbing] Univ South China, Hunan Prov Key Lab Pollut Control & Resources Reu, Hengyang 421001, Peoples R China.;[Zhang, Jie] Harbin Inst Technol, State Key Lab Urban Water Resources & Environm, Harbin 150090, Peoples R China.
通讯机构：
[Jie Zhang] S;State Key Laboratory of Urban Water Resources and Environment, Harbin Institute of Technology, Harbin 150090, China<&wdkj&>Author to whom correspondence should be addressed.
关键词：
heavy metals;wastewater treatment;industrial zones;microbial community;human health;water pollution
摘要：
Water pollution caused by heavy metals (HMs) poses a serious risk to human health and the environment and can increase the risk of diabetes, cancer, and hypertension in particular. In this study, two full-scale wastewater treatment plants (WWTPs) in industrial zones in southern China were selected to analyze the microbial community structure, diversity, similarity, and differentiation in the anoxic/oxic (AO) and anoxic/oxic membrane bioreactor (AO-MBR) units under the stress of HMs. High-throughput sequencing showed that microbial diversity and abundance were higher in the AO process than in the AO-MBR process. In the two WWTPs, the common dominant phyla were Proteobacteria and Bacteroidetes, while the common dominant genera were Gemmatimonadaceae, Anaerolineaceae, Saprospiraceae, and Terrimonas. Manganese (Mn) and zinc (Zn) positively correlated with Saccharimonadales, Nakamurella, Micrococcales, and Microtrichales, whereas copper (Cu) and iron (Fe) positively correlated with Longilinea and Ferruginibacter. Additionally, the relative abundances of Chloroflexi, Patescibacteria, and Firmicutes differed significantly (p < 0.05) between the two processes. These results may provide comprehensive outlooks on the characterization of microbial communities in WWTPs, which could also help to reduce the potential environmental risks of the effluent from WWTPs located in industrial zones.
期刊：
Asia-Pacific Journal of Oncology Nursing,2022年9(8):100073 ISSN：2347-5625
通讯作者：
Xianghua Xu
作者机构：
[Chen, Hong; Ou, Meijun] Cent South Univ, Hunan Canc Hosp, Head & Neck Surg Dept, Affiliated Canc Hosp,Xiangya Sch, Changsha, Peoples R China.;[Wang, Guifen] Univ South China, Sch Nursing, Hengyang, Peoples R China.;[Yan, Yixia] Cent South Univ, Xiangya Sch Nursing, Changsha, Peoples R China.;[Xu, Xianghua] Cent South Univ, Hlth Serv Ctr, Hunan Canc Hosp, Affiliated Canc Hosp Xiangya,Sch Med, Changsha, Peoples R China.
通讯机构：
[Xianghua Xu] H;Health Service Center, Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, China
关键词：
Oral cancer;Symptom burden;Surgical treatment;Longitudinal study
期刊：
Progress in Nuclear Energy,2022年144:104086 ISSN：0149-1970
通讯作者：
Pengcheng Li
作者机构：
[Luo, Zhuhua; Li, Pengcheng; Liu, Yahua; Dai, Licao] Univ South China, Sch Resources Environm & Safety Engn, Hengyang 421001, Hunan, Peoples R China.;[Jin, Xiao; Luo, Zhuhua; Li, Pengcheng; Liu, Yahua; Liu, Zhen; Dai, Licao] Univ South China, Human Factor Inst, Hengyang 421001, Hunan, Peoples R China.
通讯机构：
[Pengcheng Li] S;School of Resources, Environment and Safety Engineering, University of South China, Hengyang 421001, Hunan, People's Republic of China<&wdkj&>Human Factor Institute, University of South China, Hengyang 421001, Hunan, People's Republic of China
关键词：
Team situation awareness;Human reliability analysis;Dynamic Bayesian network;Digital nuclear power plants
摘要：
Team situation awareness (TSA) reliability is an important factor for team reliability. Moreover, situation awareness (SA) is a prominent problem in digital nuclear power plants (NPPs). Currently, since there is no suitable method to dynamically assess TSA reliability, we constructed a dynamical assessment method of TSA reliability based on a dynamic Bayesian network (DBN) to evaluate TSA reliability. First of all, a TSA causal concept model through qualitative analysis, expert group discussion and sample data analysis. On this basis, the quantitative assessment method of TSA reliability was constructed based on DBN and obtained probability distribution of variables. A standardized method was established to obtain the probability distribution of variables. Furthermore, we evaluated TSA dynamic reliability in a steam generator tube rupture (SGTR) accident. The results showed that the error probability of TSA decreased, and the level of TSA reliability continuously increased in SGTR. TSA reliability can be dynamically predicted by causal reasoning, the most important cause of TSA error could be identified by diagnostic reasoning, which provided theoretical support for the targeted prevention of human error. Finally, this established method was proved to be reasonable through sensitivity analysis.
