版权说明 操作指南
首页 > 成果 > 详情

Ultrasensitive detection of uranyl by graphene oxide-based background reduction and RCDzyme-based enzyme strand recycling signal amplification

认领
导出
下载 Link by DOI
反馈
分享
QQ微信 微博
成果类型:
期刊论文
作者:
Li, Ming-Hui;Wang, Yong-Sheng*;Cao, Jin-Xiu;Chen, Si-Han;Tang, Xian;...
通讯作者:
Wang, Yong-Sheng
作者机构:
[Chen, Si-Han; Li, Ming-Hui; Tang, Xian; Cao, Jin-Xiu; Zhu, Yu-Feng; Wang, Yong-Sheng; Huang, Yan-Qin; Zhu, Xiao-Feng] Univ South China, Coll Publ Hlth, Hengyang 421001, Peoples R China.
通讯机构:
[Wang, Yong-Sheng] U
Univ South China, Coll Publ Hlth, Hengyang 421001, Peoples R China.
语种:
英文
关键词:
Enzyme strand recycling amplification;G-quadruplexes;Graphene oxide;N-methyl- mesoporphyrin IX;RNA-cleaving chimera DNAzyme;Zero-background signal
期刊:
Biosensors and Bioelectronics
ISSN:
0956-5663
年:
2015
卷:
72
页码:
294-299
基金类别:
The authors gratefully acknowledge the support of the National Natural Science Foundation of China (No. 21177052 ), the Science and Technology Program of Hunan Province in China (No. 2010SK3039 ) and the Construct Program of the Key Discipline (Public Health and Preventive Medicine) in Hunan Province.
机构署名:
本校为第一且通讯机构
院系归属:
公共卫生学院
摘要:
We proposed a novel strategy which combines graphene oxide-based background reduction with RCDzyme-based enzyme strand recycling amplification for ultrahigh sensitive detection of uranyl. The RCDzyme is designed to contain a guanine (G)-rich sequence that replaces the partial sequence in an uranyl-specific DNAzyme. This multifunctional probe can act as the target recognition element, DNAzyme and the primer of signal amplification. The presence of UO22+ can induce the cleavage of the substrate strands in RCDzyme. Then, each released enzyme stran...

反馈

验证码:
看不清楚,换一个
确定
取消

成果认领

标题:
用户 作者 通讯作者
请选择
请选择
确定
取消

提示

该栏目需要登录且有访问权限才可以访问

如果您有访问权限,请直接 登录访问

如果您没有访问权限,请联系管理员申请开通

管理员联系邮箱:yun@hnwdkj.com